Cj Cheiljedang Corporation

Metabolix, Inc.

Jeffrey A Bickmeier

Thomas Martin Ramseier

Yossef Shabtai

William R Farmer

Oliver P Peoples

Frank Anthony Skraly

Johan Van Walsem

Erik Anderson

Christopher L Mirley

Kevin A Sparks

John Licata

Catherine Morse

Himani Chinnapen

Ann D'Ambruoso

Melarkode S Sivasubramanian

Thomas M Ramseier

A polyhydroxyalkanoate copolymer composition is provided. The composition comprises a plurality of polyhydroxyalkanoate copolymer molecules. The polyhydroxyalkanoate copolymer molecules (i) comprise 3-hydroxybutyrate monomers and 4-hydroxybutyrate monomers, (ii) have a monomeric molar percentage of 4-hydroxybutyrate monomers of 23.5 to 75%, and (iii) have a biobased content of &#x2265;80%. Also provided is a method of making a polyhydroxyalkanoate copolymer composition. The method comprises culturing an organism in the presence of one or more carbon raw materials under conditions under which (a) the one or more carbon raw materials are converted to 3-hydroxybutyryl-CoA and 4-hydroxybutyryl-CoA and (b) the 3-hydroxybutyryl-CoA and the 4-hydroxybutyryl-CoA are polymerized to form the polyhydroxyalkanoate copolymer molecules, thereby forming the composition. The organism has been genetically engineered to comprise particular enzymatic activities, and to not comprise other particular enzymatic activities. The one or more carbon raw materials, taken together, have a biobased content of &#x2265;80%.

Polyhydroxyalkanoate copolymer compositions and methods of making the same

Processes and methods for making biobased gamma-butyrolactone from renewable carbon resources are described herein.

Process for gamma-butyrolactone production

Growing community of inventors

Arlington, MA, United States of America

Jeffrey A Bickmeier