Diakron Pharmaceuticals, Inc.

Amylin Pharmaceuticals, Inc.

Vittal Mallya Scientific Research Foundation

Vittal Mallya Scientific Research

Jeffrey A Bibbs

Pillarisetti Venkata Subbarao

Phani Kumar Pullela

Srirama Rao

Paramashivappa Rangappa

Srinivasa Rao Alapati

Howard Jones

Pillarisetti V Subbarao

Laura S Lehman De Gaeta

The present invention is directed in part towards methods of modulating the function of calcium channels with dihydropyrimidine, dihydropyrimidone, dihydropyrimidinethione, and dihydropyridine compounds. In addition, the invention describes methods of preventing and treating protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to T-channel agonists that have a slow onset of activity and long duration of activity.

Calcium channel blockers

Methods of treating a mammal with high blood-glucose, or high blood-cholesterol, levels with isovitexin, and pharmaceutical compositions comprising the same are disclosed.

Pharmaceutical compositions for lowering blood glucose and blood cholesterol levels

The present invention is directed in part towards methods of modulating the function of calcium channels with pyridine- or 1,4-dihydropyridine-based compounds. In addition, the invention describes methods of preventing and treating protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to pyridine- or 1,4-dihydropyridine-based compounds and pharmaceutical compositions comprising these compounds.

1,4-dihydropyridine and pyridine compounds as calcium channel blockers

Methods of preparing a peptide having a C-terminal amide group from peptides having a C-terminal carboxyl group are provided.

Production of peptide amides

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San Diego, CA, United States of America

Jeffrey A Bibbs