Max-planck-gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

Bayer Aktiengesellschaft

Plant Genetic Systems N.v.

Other

Basf Plant Science Gmbh

Ramot Univ. Auth. for Applied Research and Industrial Development Ltd.

Jeff Schell

John Mundy

Guido Jach

Peter Helmut Schreier

Peter Eckes

Hans J Bohnert

Marc Charles Van Montagu

Ilan Chet

Jurgen Logemann

Albert P Kausch

Luis Herrera-Estrella

Michael P Timko

Csaba Koncz

Nicolai Strizhov

Anthony R Cash More

Birgit Gornhardt

J&uuml;rgen Logemann

Guido Van Den Broeck

Reinhard Topfer

Guidi Van Den Broeck

Baruch Sneh

Hans Kosak

Birgit Görnhardt

Jürgen Logemann

Bernd Reiss

Birgit G&ouml;rnhardt

Thomas Herget

Manfred Klemm

Barbara Klein

Menachem Keller

Christoph Maas

Christa Horicke-Grandpierre

Aviah Zilberstein

Anthony R Cashmore

Hans-Henning Steinbiss

Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).

Transgenic pathogen-resistant organism

The present invention relates to a novel process for the production of transgenic organisms or transgenic cells, to transgenic orgaisms or transgenic cells obtainable by the process of the present invention, to the use of vectors comprising DNA encoding a recombination promoting enzymes for curing impairments caused by environmental influences in plants or plant cells and for gene therapy in mammals or mammalian cells, and to novel vectors.

Stimulation of homologous recombination in eukaryotic organisms or cells by recombination promoting enzymes

Described are a method of producing pathogen-resistant plants in which a protein-synthesis inhibitor gene or a fusion product of the protein-synthesis inhibitor gene or of the protein-synthesis inhibitor protein with ligands permitting specific attachment to cells is introduced into the genotype of plants under the control of an active promotor, and the use of the protein-synthesis inhibitor protein obtained by introducing the protein-synthesis inhibitor gene into the bacterial overproducers for making pharmaceutical preparations.

Method of producing pathogen-resistant plants

Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinese (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFR).

Transgenic pathogen-resistant plant

The present invention relates to DNA isolated from,which encodes or hybridizes to DNA which encodes a protein that repels pests. Such DNA is useful in the transformation of vectors, host organisms and plants and for the production of plants which exhibit an increased resistance to pests.

Resistance genes

Keto-acyl-(ACP) reductase promoter from cuphea lanceolata

A method of gene synthesis is disclosed. The gene synthesis method permits the codons of [m] natural gene to be changed to allow preferential transcription and translation of the synthetic gene in transgenic organisms. The method utilizes a combination of enzymatic and chemical synthesis of DNA and significantly reduces the cost, time and number of steps required for construction of synthetic genes.

Gene synthesis method

Chimaeric DNA sequence which encodes: 1) a transit peptide of a cytoplasmic precursor of a chloroplast protein or polypeptide of a plant and 2) a protein or polypeptide that is heterologous to the transit peptide. The chimaeric DNA sequence can be used as a vector for transforming a plant cell so that a chimaeric precursor of the heterologous protein or polypeptide is produced in the cytoplasm of the cell and the chimaeric precursor then transports the heterologous protein or polypeptide in vivo into a chloroplast of the cell.

Chimaeric gene coding for a transit peptide and a heterologous peptide

The present invention relateds to a synthetic version of a gene isolated from Bacillus thuringiensis encoding an insectidical crystal protein designated CryIC, plants transformed with the gene, and the insecticidal crystal protein toxin expressed by the gene, all of which are used to control insects of the Spodoptera species as well as those of the Mamestra species.

Synthetic Bacillus thuringiensis cryic gene encoding insect toxin

Modular promoter construct

Chimaeric gene coding for a transit peptide and a heterologous

Growing community of inventors

Koln, Germany

Jeff Schell