Advanced Cardiovascular Systems, Inc.

Abbott Cardiovascular Systems, Inc.

Jeff Royal

Syed F A Hossainy

Ty T Hu

Kurt W Scheinpflug

Dorie M Happ

Stephen D Pacetti

Paul M Consigny

Fuh-Wei Tang

Gordon S Stewart

Mark A Williams

Dorrie M Happ

Ty Hu

Syed FA Hossainy

Gordon C Stewart

A method of coating a stent is presented such that less than 50% of the total amount of 40-O-(2-hydroxyl)ethyl-rapamycin, or an analog or derivative thereof, is released in vivo in a 24 hour period, wherein the method comprises exposing the coating to sufficient temperature to modify the structure of the polymer.

Method of coating a stent with a release polymer for 40-O-(2-hydroxy)ethyl-rapamycin

A method and coating for reducing the release rate of an active agent from an implantable device, such as a stent, is disclosed.

40-O-(2-hydroxy)ethyl-rapamycin coated stent

A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition such as a temperature above the glass transition temperature of a polymer included in the coating.

Thermal treatment of a drug eluting implantable medical device

A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition which can result in reduction of the rate of release of an active agent from the coating subsequent to the implantation of the device.

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San Francisco, CA, United States of America

Jeff Royal