Corixa Corporation

Infectious Disease Research Institute

Jeff Guderian

Steven G Reed

Yasir A Skeiky

Yasir A W Skeiky

Ajay Bhatia

Malcolm Duthie

Jean-Francois Lucien Maisonneuve

Compositions and methods for preventing, treating and detecting leishmaniasis are disclosed. The compositions generally comprise polypeptides comprisingantigens as well as polynucleotides encoding such polypeptides.

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The present invention relates to compositions and fusion proteins containing at least twosp. antigens, and nucleic acids encoding such compositions and fusion proteins. The compositions of the invention increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection.

Fusion proteins of mycobacterium tuberculosis

Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of aantigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

Compounds and methods for treatment and diagnosis of chlamydial infection

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Lynwood, WA, United States of America

Jeff Guderian