Atreca, Inc.

Jeff DeFalco

Wayne Volkmuth

Shaun M Lippow

Daniel Eric Emerling

Tito Serafini

William H Robinson

Yann Chong Tan

Sean Matthew Carroll

Jessica Finn

Norman Michael Greenberg

Vera Huang

Fengling Liu

Amy Manning-Bog

Norm Greenberg

Alexander Scholz

Nikhil Vad

Provided herein are antibodies that bind to tumor tissue through a binding interaction with an extracellular RNA-protein complex. Such antibodies are used in methods of inducing an immune response and methods of inhibiting tumor cell growth. Additionally provided are methods of producing such antibodies.

Antibodies that bind tumor tissue for diagnosis and therapy

Disclosed herein are methods and compositions for using nanoexpression to interrogate antigen specificity within antibody repertoires. Also disclosed herein is an antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence.

Use of nanoexpression to interrogate antibody repertoires

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Foster City, CA, United States of America

Jeff DeFalco