Intron Biotechnology, Inc.

Jeesoo Son

Sanghyeon Kang

Seongjun Yoon

Yunjaie Choi

Sooyoun Jun

Hyoungrok Paik

Seabong Kyoung

Seyung Lee

Se Yung Lee

Se Jung Lee

The present invention relates to a composition comprising EK99P-1, a bacteriophage isolated from nature and capable of infectingtype K99 so as to kill the same, as an active ingredient, and a method for preventing and treatingtype K99 infections using the said composition. According to the present invention, the bacteriophage EK99P-1, an active ingredient of the composition, has a killing activity againsttype K99 and has the genome represented by SEQ. ID. NO: 1.

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The present invention relates to compositions for removing a biofilm formed by, comprising a, such as Myoviridae family T4-like phage genus(Accession No: KCTC 11153BP, SAP-1) or Podoviridae family &#x3c6;29-like virus genus(Accession No: KCTC11154BP, SAP-2), and lytic protein derived therefrom, that destroys the biofilm. Also disclosed are pharmaceutical compositions for the treatment of diseases caused bycapable of forming biofilm.

The present invention relates to a novel antimicrobial protein derived from bacteriophage having killing activity specific to, more precisely an antimicrobial protein originated from Podoviridae bacteriophage having killing activity specific towhich is the causing agent of infectious disease in human and animals, a pharmaceutical composition for the prevention and treatment of infectious disease caused by, an antibiotic and a disinfectant containing the bacteriophage-originated antimicrobial protein as an active ingredient.

The present invention relates to a composition for the treatment of ballast water containing bacteriophage capable of killing specific target bacteria as an active ingredient in order to eliminate or reduce bacteria including pathogenic bacteria present in ballast water, and a biological treatment method of ballast water.

Composition for the treatment of ballast water containing bacteriophage as an effective component and biological method with the same for removing bacteria present in ballast water

The present invention relates to a novel bacteriophage-originated protein having antimicrobial activity, more precisely an antimicrobial protein originated from lytic bacteriophage having killing activity specific towhich is the causing agent of infectious diseases in human and animals, a pharmaceutical composition for the prevention and treatment of the disease caused by, an antibiotic and a disinfectant containing the bacteriophage-originated antimicrobial protein as an active ingredient.

The present invention relates to a novel bacteriophage, more precisely a novel bacteriophage having killing activity specific towhich is the causing agent of infectious diseases in human and animals, a pharmaceutical composition for the prevention and treatment of the disease caused by, an antibiotic and a disinfectant containing the bacteriophage as an active ingredient.

The present invention relates to a lysin protein originated from bacteriophage, more precisely a lysin protein comprising the amino acid sequence represented by SEQ. ID. NO: 2 which has no harm to human and animals comprising eukaryotic cells owing to its specificity to bacteria and has broad antibacterial activity, and a pharmaceutical composition for the prevention and treatment of infectious disease caused by bacteria comprising the said lysin protein as an active ingredient.

Lysin protein having broad antibacterial activity specific to bacteria

The present invention relates to a novel bacteriophage, more precisely a Podoviridae bacteriophage having killing activity specific towhich is the causing agent of infectious disease in human and animals, a pharmaceutical composition for the prevention and treatment of the disease caused by, an antibiotic and a disinfectant containing the bacteriophage as an active ingredient.

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Seoul, South Korea

Jeesoo Son