Neuracle Genetics Inc.

Jee Yong Kim

Jong-Mook Kim

Joo Seok Han

Hoon Young Kong

Sunhwa Shin

Kyungwon Lee

Novel intron fragments are provided. The intron fragments can increase gene expression to levels equal to or higher than those achieved by the full-length intron while maintaining their ability to increase gene expression even when combined with various types of promoters and splicing donors. Particularly, the intron fragments enable loading of larger transgenes when used in genetic information delivery systems whose size is limited, for example, adeno-associated viruses (AAVs) and rhabdoviruses. Therefore, the use of the intron fragments is expected to extend the range of therapeutic genes.

Growing community of inventors

Gwacheon-si, South Korea

Jee Yong Kim