Co.don Ag

Co.don Aktiengesllschaft

Jeanette Libera

Olivera Josimovic-Alasevic

Karl-Gerd Fritsch

Vilma Siodla

Hans-Joerg Meisel

Ursula Anderer

Vilma Methner

The invention relates to a method for the in vitro production of intervertebral disk cartilage cell transplants from affected intervertebral disk tissue from patients and to the use thereof as transplantation material for the treatment of affected intervertebral disks. The invention also relates to a three-dimensional, vital, and mechanically stable intervertebral disk cartilage tissue and to the use thereof as transplantation material for the treatment of affected intervertebral disks and in testing active substances. Furthermore, the invention is directed to the surgical technique for incorporating the transplants, to the intervertebral disk cell transplants and intervertebral disk cartilage tissues produced, and to therapeutic formulations, e.g. injection solutions, which include said tissue and said cell transplants.

Method for the production of intervertebral disk cell transplants and their use as transplantation material

The invention relates to a remarkably simple method for the in vitro production of three-dimensional, vital and mechanically stable cartilage or bone tissue and to the use thereof as a transplantation material for treating cartilage or bone defects and degenerative diseases such as rheumatism or arthrosis, and to the use thereof in testing active substances and physical factors. The invention is also directed to the cartilage or bone tissue and therapeutical formulations produced thereby, e.g. injection solutions comprising such tissue.

Method for in vitro production of three-dimensional vital cartilage tissue and use thereof as transplant material

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Berlin, Germany

Jeanette Libera