Endorecherche, Inc.

Valorisation Recherche Hscm, Limited Partnership

Jean-Yves Sancéau

Fernand Labrie

Sylvain Gauthier

René Maltais

Steeves Potvin

Julie Cloutier

Josée Mailhot

Sylvain Dion

Mohamed Benderdour

Julio Fernandes

The present application relates to resolvin analogs having anti-inflammatory and antioxidant properties, uses and methods using the same. More specifically, the present application relates to compounds of formula (I) or an enantiomer, isomer, salt or solvate thereof.

Resolvin analogs compounds, methods and uses thereof

Compounds having the structure, their salts or N-oxide derivatives: are used to treat or reduce le likelihood of acquiring androgen-dependent diseases, such as prostate cancer, benign prostatic hyperplasia, polycystic ovarian syndrome, acne, hirsutism, seborrhea, androgenic alopecia and male baldness. They can be formulated together with pharmaceutically acceptable diluent or carrier or otherwise made into any pharmaceutical dosage form. Combinations with other active pharmaceutical agents are also disclosed.

17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators

Growing community of inventors

Québec, Canada

Jean-Yves Sancéau