Leland Stanford Junior University

The United States Government As Represented by the Department of Veterans Affairs

Children's Hospital & Research Center Oakland

Jean Tang

M Peter Marinkovich

Alfred T Lane

Paul A Khavari

Zurab Siprashvili

Ngon T Nguyen

Philip Arden Beachy

Jayakumar Rajadas

Ervin H Epstein, Jr

Gilbert Chu

Robert Tibshirani

Wan-Jen Hong

Virginia Goss Tusher

James Kim

Kerri Elyse Rieger

Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet.

Gene therapy for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes

Methods of transdermally delivering a therapeutic amount of a triazole-triazolone compound are provided, e.g. for the prevention or treatment of basal cell carcinoma (BCC) in a subject. A therapeutic level of a triazole-triazolone compound such as itraconazole is delivered transdermally to a subject. Also provided are topical triazole-triazolone compositions that find use in practicing the subject methods.

Topical itraconazole formulations and uses thereof

Methods are provided for determining whether a patient treated with an anti-proliferative agent is susceptible to toxicity. In practicing the subject methods, an expression profile for the transcriptional response to a therapy is obtained from the patient and compared to a reference profile to determine whether the patient is susceptible to toxicity. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.

Methods and compositions for determining risk of treatment toxicity

Growing community of inventors

Mountain View, CA, United States of America

Jean Tang