Centre National De La Recherche Scientifique

Institut National Polytechnique De Toulouse

Bioland Ltd.

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Centre De Cooperation Internationale En Recherche Agronomique Pour Le Developpement

Jean-Stéphane Condoret

Alain Marty

Suzelei Montanari

Daniel Samain

Jacques Fages

Didier Combes

Guillaume Boissonnet

Jean-Michel Commandre

Philippe Destrac

Christophe Gourdon

Michel Vignon

Capucine Dupont

Xuan Meyer

Michel Meyer

Kim Le Thanh

Mylène Detcheberry

The invention relates to a method for the controlled oxidation of oligo- and/or polysaccharides containing free &#x2014;CHOH primary hydroxyl groups, using an oxidizing agent. The invention is characterized in that the oxidation reaction is performed in a densified fluid which is inert in relation to the oxidizing agents employed. The invention is suitable for use, for example, in the food, paint, paper, textile, agricultural and pharmaceutical industries, in the medical, biomedical or paramedical fields, in the surgical field, in the cosmetic industry and as agents for the complexing or sequestering of metal ions, heavy metals and radioactive elements in the nuclear industry.

Method for the controlled oxidation of polysaccharides

The present invention concerns a process for treating bone tissue of animal or human origin, and a corresponding implantable biomaterial. According to the present invention, a fluid in the supercritical state is caused to penetrate throughout the bone tissue. The bone tissue thus treated can then undergo stages of extracting specific proteins. This tissue is intended to be placed on a damaged bone tissue and has mechanical properties at least equivalent to those of natural bone.

Process for treating bone tissue and corresponding implantable

Growing community of inventors

Toulouse, France

Jean-Stéphane Condoret