Columbia University

Jean Provost

Elisa E Konofagou

Stanley J Okrasinski

Stéphane Thiébaut

Jianwen Luo

Vu Thanh-Hieu Nguyen

Julien Grondin

Elaine Wan

Gary Yi Hou

Jiangang Chen

Alok Gambhir

Alexandre Costet

Ultrasound methods, devices, and systems are described which support a useful compromise in terms of spatial resolution and temporal resolution for capturing motion in tissue structures. Tissue engineering articles, methods, systems, and devices which employ ultrasound to deliver biological agents to selected regions of a tissue scaffold, deliver mechanical stimulation to cells growing in a tissue scaffold, and enhance the perfusion of fluids through tissue scaffolds.

Ultrasound devices methods and systems

Systems and methods for detecting electromechanical wave propagation within a body structure of a patient in a series of image frames representing movement the body structure are provided. Image data is acquired comprising a series of image frames corresponding to the movement of a body structure. A correlation calculation is performed on the image frames to generate a displacement map representing the relative displacement between the first and second image frames. A video is generated comprising a series of displacement maps. The parameters of movement of the body structure are detected by analysis of the displacement maps. The image acquisition can detect the movement of the body structure without inducing such movement.

System and method for electromechanical activation of arrhythmias

Techniques for mapping behavior of a heart include acquiring a series of two or more images of the heart. The series of images is taken at one or more pixel locations, each pixel location corresponding to a region of the heart. Image data corresponding to the pixel locations can be obtained, and a periodicity of the image data measured for each of the pixel locations over the series of images. The periodicity corresponds to an electromechanical signal of the heart in the region corresponding to the measured one or more pixel locations.

Systems and methods for mechanical mapping of cardiac rhythm

Systems and methods for matching a characteristic of multiple sectors of a moving tissue to verify an overlap thereof are disclosed herein. In an exemplary method, tissue data for at least a first sector and a second sector of a moving tissue is acquired. A characteristic of at least a portion of the first and second sectors is estimated from the acquired tissue data, and the estimated characteristics are matched to verify whether a portion of the first sector overlaps with a portion of the second sector. Estimating can include estimating a displacement such as an axial displacement and/or lateral displacements. Estimating can further include estimating a strain, a velocity, a strain rate and/or a stiffness or equivalent.

Systems and methods for matching and imaging tissue characteristics

Systems and techniques of treatment monitoring include acquiring channel data from each of a plurality of channels of a signal array over a plurality of frames, determining a reconstruction matrix based on a reconstruction operation to be performed on the channel data, applying the reconstruction matrix to the channel data to obtain reconstructed channel data, estimating displacement data representing displacement of an object over the frames from the reconstructed channel data; determining a conversion matrix based on a conversion operation to be performed on the reconstructed channel data, and applying the conversion matrix to the reconstructed channel data to obtain a displacement map.

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New York, NY, United States of America

Jean Provost