Pierre Fabre S.a.

Pierre Fabre Medicament

Other

Jean-Pierre Tarayre

Henri Cousse

Silvano Casadio

Gilbert Mouzin

Dennis C Bigg

Bernard Bonnaud

Bernard Vacher

Jean-Pierre Rieu

Wouter Koek

Francis Colpaert

Jean-Francois Patoiseau

Jean-Marie Autin

Guy Pitet

Christian Faure

Francoise Couret

Henri Lauressergues

Liesbeth Bruins Slot

Henry Cousse

Gilbert Alphonse Morales, Legal Representative

The invention concerns the use pf compounds of general formula (I) for treating opioid drug dependence, hyperalgesia induced by opiate drug withdrawal and psychological craving induced by opiate drug withdrawal.

Pyridin-2-yl-methylamine derivatives for treating opiate dependence

1,2-dihydro-2-oxo-3-aminoquinoxaline derivatives, their preparation and

Derivatives of 1,2-dihydro 2-oxo quinoxalines, their preparation and

This invention relates to new derivatives of biphenyl alkyl carboxylates, to a process for the preparation thereof and the use thereof as medicaments. The new derivatives according to the present invention correspond to general formula (I): ##STR1## wherein X represents a hydrogen atom or a halogen atom,

Derivatives of biphenyl alkyl carboxylates and their use as medicaments

The present invention relates to new derivatives of 4-phenyl-2-thiazolyl oxamates having the formula: ##STR1## in which: X represents hydrogen, halogen, lower-alkyl, or lower-alkoxy.

4-Phenyl-2-thiazolyl-oxamates useful in the treatment of asthma

The present invention concerns new derivatives of 4-phenyl 2-amino thiazole of the formula ##STR1## in which X represents a hydrogen atom, a halogen, a lower alkyl or an alkoxy,

Immunoactivators derived from amino thiazoles

New chemical compounds, which are pyrrolidinoethylamine amides, in the form of free bases and salts thereof, which are useful as antitussives, pharmaceutical compositions thereof, and method of treating therewith. In the form of their salts, the compounds have the formula: ##STR1## wherein ##STR2## is an acyl radical of a phenylacetic,.alpha.-phenyl-.alpha.-ethylacetic, diphenylacetic, benzilic, .alpha.-lower-alkoxy-.alpha.,.alpha.-diphenylacetic, 10-phenothiazinecarboxylic, benzoic, halobenzoic, 3-coumarincarboxylic, 9-xanthenecarboxylic, salicylic, cresotic, halocresotic, lower-alkoxybenzoic, phenoxyacetic, phenoxyisobutyric, halophenoxyisobutyric, cinnamic, or 9-fluorene carboxylic acid, and wherein R'H represents an inorganic or organic acid, and wherein R may be, for example, a substituted aromatic ring of the formula: ##STR3## wherein R.sub.1 and R.sub.2 may independently be lower-alkyl, lower-alkoxy, hydrogen, lower-alkenyloxy, or lower-alkynyloxy, and X may be hydrogen or halogen. Medicaments containing these active principles may be used, inter alia, in the treatment of coughs and respiratory complaints.

Amides of pyrrolidinoethylamine which can be used in lung therapy

New chemical compounds, which are pyrrolidinoethylamine amides, in the form of free bases and salts thereof, which are useful as antitussives, pharmaceutical compositions thereof, and method of treating therewith. In the form of their salts, the compounds have the formula: ##STR1## wherein ##STR2## is an acyl radical of a phenylacetic, 60 -phenyl-.alpha.-(1 to 5 C atoms) acetic, (1 to 5 C atoms) diphenylacetic, benzilic, diphenyl-.alpha.-chloroacetic, .alpha.-lower-alkoxy-.alpha.,.alpha.-diphenylacetic, 3-coumarincarboxylic, 9-xanthenecarboxylic, phenoxyacetic, phenoxyisobutyric, halophenoxyisobutyric, or 9-flourene carboxylic acid, and wherein R'H represents an inorganic or organic acid. Medicaments containing these active principles may be used, inter alia, in the treatment of coughs and respiratory complaints.

Amides of pyrrolidinoethylamine which can be used in treatment of coughs

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Castres, France

Jean-Pierre Tarayre