Sadra Medical, Inc.

Boston Scientific Scimed, Inc.

Twelve, Inc.

Shifamed Holdings, LLC

Medtronic, Inc.

Endologix, Inc.

Kalila Medical, Inc.

Jean-Pierre Dueri

Amr Salahieh

Dwight P Morejohn

Brian D Brandt

Hans F Valencia

Ulrich R Haug

Robert Adam Geshlider

Tom Saul

Jeff A Krolik

John H Morriss

Daniel K Hildebrand

Hanson Gifford

Claudio Argento

Matt McLean

Michael Luna

Jonah Lepak

Darin Charles Gittings

David Jerry Scott

James I Fann

David Trask

Maureen Bensing

Kirsten Valley

Katie Miyashiro

Mark E Deem

Douglas Sutton

Clayton Baldwin

Brice Arnault De La Menardiere

Emma Lepak

Andrea Johnson

Matt Mclean

Jeffry J Grainger

Emma Leung

Hanson S Gifford, Iii

Douglas S Sutton

Richard Joseph Renati

Matthew McLean

Joseph Creagan Trautman

Finn Olavi Rinne

Christopher T Cheng

Gavin Kenny

Colin Mixter

Yogesh Darekar

Elliot J Howard

Jason Fox

Priya Nair

Cahal Mcveigh

George N Hallak

William Jason Fox

TOm Saul

Marc Bitoun

Brenda L McIntire

Jeffrey J Grainger

James L Fann

Steve Herbowy

Darrin Gittings

Hanson Iii Gifford

Mark Deem

Yogesh A Darekar

Brenda L Mcintire

A heart valve repair device may include a support configured to extend through a native annulus of a native heart valve, wherein the support comprises an upstream portion and a downstream portion; an annular expandable retainer extending from the upstream portion of the support, and an arm extending from the downstream portion of the support. The annular expandable retainer may include a C-shaped cross-section that is open inwardly. The arm may be configured to reach behind a leaflet of the native heart valve and sandwich the leaflet between the arm and the support.

Devices, systems and methods for heart valve replacement

A flow diversion device configured in accordance with embodiments of the present technology may include, for example, a housing including openings to channels that intersect at a junction. The flow diversion device may also include, for example, a flow control component disposed at the junction and movable to selectively form pathways for fluid communication based on a position of the flow control component. For example, when the flow control component is in a first position, a first pathway may allow fluid flow causing deployment of the prosthetic heart valve device and, when the flow control component is in a second position, a second pathway may allow fluid flow causing recapture of the prosthetic heart valve device. The flow diversion device may include a handle movable to position the flow control component in the first or second positions thereby selectively controlling fluid flow of the delivery system.

Hydraulic delivery systems with flow diversion devices and associated methods

The devices and methods of this disclosure relate to a heart valve prosthesis that is configured to be implanted within a native heart valve having a smaller perimeter annuli with a generally elliptical shape.

Compact prosthetic heart valve device

Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.

Replacement valve and anchor

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.

Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods

The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.

Methods and apparatus for endovascularly replacing a heart valve

Steerable medical devices and methods of use. In some embodiments, the steerable medical devices can be steered bi-directionally. In some embodiments the steerable medical devices include a first flexible tubular member and a second flexible tubular member secured together at a location distal to a steerable portion of the steerable medical device.

Steerable medical devices, systems, and methods of use

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having a first portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a valve support coupled to a second portion of the anchoring member, configured to support a prosthetic valve and having a cross-sectional shape. In some embodiments, the first portion of the anchoring member is mechanically isolated from the valve support such that the cross-sectional shape of the valve support remains sufficiently stable that the prosthetic valve remains competent when the anchoring member is deformed in the non-circular shape.

Growing community of inventors

Los Gatos, CA, United States of America

Jean-Pierre Dueri