Micro-pak, Inc.

Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Jean Philippot

Donald F Wallach

Rajiv Mathur

Surendra Kumar

Jean-Pierre Liautard

An antacid product having extended duration of residence in the gastric and upper intestinal systems has been developed. This antacid product includes a blend of 10-70% by volume nonphospholipid lipid vesicles, with a particulate base. An antiflatulence agent may also be included. A method of providing extended duration amelioration of acid build up in the gastric and upper intestinal tract using this product is also disclosed.

Extended duration antacid product

Disclosed is a new type of unilamellar lipid vesicle made from polyoxyethylene acyl ethers or sorbitan alkyl esters. These unilamellar vesicles are made with easily obtained, relatively inexpensive materials and the vesicles are more stable then conventional unilamellar lipid vesicles. A delivery system for drugs or other molecules is also disclosed.

Method of manufacturing unilamellar lipid vesicles

Device for obtaining and administering unilamellar liposomes

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St Clement La Riviere, France

Jean Philippot