Centre National De La Recherche Scientifique

Universitè De Montpellier

Université Montpellier 2 Sciences Et Techniques

Centre National De La Recherche Scientifique-cnrs

Université Montpellier I

Jean-Philippe Biron

Hervé Cottet

Luca Cipelletti

Michel Martin

Suzanne Anouti

Odile Trambouze

A method for determining the size distribution of a mixture of molecule or particle species including the steps of: injecting a sample of the mixture to be analyzed inside a capillary in which an eluent is flowing; transporting the sample injected along the capillary from an injection section to a detection section thereof, in experimental conditions suitable to generate a Taylor dispersion phenomenon that is measurable at the level of the detection section; generating, by a suitable sensor included in the detection section, a signal characteristic of the Taylor dispersion of the transported sample; processing the detection signal in order to obtain an experimental Taylor signal S(t); and analyzing the experimental Taylor signal &#x15c;(t), wherein the step of analyzing an experimental Taylor signal &#x15c;(t) of a sample of the mixture consists of searching an amplitude distribution P(G) that allows the experimental Taylor signal &#x15c;(t)' to be broken down into a sum of Gaussian functions.

Method for determining the size distribution of a mixture of particles using Taylor dispersion, and associated system

A method for separating the constituents of a mixture M by electrophoresis in a single capillary includes (A) separating compounds of the mixture M in a single capillary according to the capillary electrophoresis technique; (B) isolating a fraction F of the compounds thus separated by evacuating part of the compounds having the highest migration speeds from the capillary and/or evacuating part of the compounds having the lowest migration speeds from the capillary; (C) introducing a separating medium MS having a higher migration speed than the compounds of the isolated fraction F into the capillary containing the isolated fraction F, and (D) the compounds contained in fraction F are separated in the new electrophoretic conditions thus obtained.

Bidimensional separation by means of capillary electrophoresis carried out in a single capillary

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Saint Gely du Fesc, France

Jean-Philippe Biron