The Johns Hopkins University

Jean-Paul Wolinsky

Jeffrey H Siewerdsen

Dan Stoianovici

Ali Uneri

Michael Ketcha

Wathudurage Tharindu deSilva

Yoshito Otake

Daniel Stoianovici

Sureerat Reaungamornrat

Wathudurage Tharindu De Silva

Featured is a vertebral body manipulation instrument or vertebral body manipulation device being configured and arranged to allow correction of vertebral translation. Such a vertebral body manipulation device embodies one or more identical modules that are configured as needed for correcting the deformity. Such a vertebral body manipulation device also is usable in combination with a plurality of vertebral anchors, such vertebral anchors being any such vertebral anchors as are known to those skilled in the art (e.g., conventional spinal pedicle screw instrumentation) or hereinafter developed so as to form a spinal implant system. Also featured are treatment methods utilizing such a vertebral body manipulation device.

Vertebral body manipulation device and methods

An embodiment in accordance with the present invention provides a method for 3D-2D registration (for example, registration of a 3D CT image to a 2D radiograph) that permits deformable motion between structures defined in the 3D image based on a series of locally rigid transformations. This invention utilizes predefined annotations in 3D images (e.g., the location of anatomical features of interest) to perform multiple locally rigid registrations that yield improved accuracy in aligning structures that have undergone deformation between the acquisition of the 3D and 2D images (e.g., a preoperative CT compared to an intraoperative radiograph). The 3D image is divided into subregions that are masked according to the annotations, and the registration is computed simultaneously for each divided region by incorporating a volumetric masking method within the 3D-2D registration process.

Method for deformable 3D-2D registration using multiple locally rigid registrations

An embodiment in accordance with the present invention provides a technique for localizing structures of interest in projection images (e.g., x-ray projection radiographs or fluoroscopy) based on structures defined in a preoperative 3D image (e.g., MR or CT). Applications include, but are not limited to, spinal interventions. The present invention achieves 3D-2D image registration (and particularly allowing use with a preoperative MR image) by segmenting the structures of interest in the preoperative 3D image and generating a simulated projection of the segmented structures to be aligned with the 2D projection image. Other applications include various clinical scenarios involving 3D-2D image registration, such as image-guided cranial neurosurgery, orthopedic surgery, biopsy, and radiation therapy.

MR-levelcheck-2: method for localization of structures in projection images

The Vertebral Osteotomy Saw Guide allows precise osteotomies to be performed through the vertebral column in conjunction with a thread-wire saw. The guide is designed so that it can mount to rods commonly used during spinal surgery for spinal stabilization. The mount of the guide is a polyaxial mount, allowing the angle of the guide mount to be adjusted and locked to create a desired cutting plane to produce a precise osteotomy. The guide itself consists of two interdigitated pulley wheels that allow the thread-wire saw to pass smoothly through the guide. The simple, but unique design of the guide allows a surgeon to perform an osteotomy through the vertebral column cutting from one side of the vertebral column to the other. This unique orientation allows the osteotomy to be performed away from critical structures in the region (the spinal cord, aorta, and inferior vena cava).

Vetebral osteotomy saw guide

A method of 3D-2D registration for medical imaging includes the following steps: providing a first input interface for acquiring a three-dimensional image; providing a second input interface for acquiring a fixed two-dimensional image using an imaging system that includes a source and a detector and that has an unknown source-detector geometry; initializing image transformation parameters and source-detector geometry parameters; generating a reconstructed two-dimensional image from the three-dimensional image using the image transformation parameters and the source-detector geometry parameters; determining an image similarity metric between the fixed two-dimensional image and the reconstructed two-dimensional image; and updating the image transformation parameters and the source-detector geometry parameters using the image similarity metric, and a corresponding non-transitory computer-readable medium and apparatus.

3D-2D image registration for medical imaging

Featured is a reduction instrument being configured and arranged to allow correction of vertebral translation and applying distraction across a segment in an independent fashion. Such a reduction instrument embodies one or more identical modules that are configured as needed for correcting the deformity. In more particular embodiments, each of the one or more modules has two degrees of freedom (DOF) with uncoupled orthogonal translations. Such a reduction instrument allows the reorientation of the vertebral segment as needed via uncoupled orthogonal translations. Such a reduction instrument also is usable in combination with a plurality of vertebral anchors, such vertebral anchors being any such vertebral anchors as are know to those skilled in the art (e.g., conventional spinal pedicle screw instrumentation) or hereinafter developed so as to form a spinal implant system. Also featured are treatment methods utilizing such a reduction instrument.

Growing community of inventors

Towson, MD, United States of America

Jean-Paul Wolinsky