La Calhene, Inc.

Jean-Michel Riviere

Philippe Fontcuberta

Jean-Pierre Brossard

Patrick Senges

Sterile products contained in a container (,) are transferred into a sterile isolator (,) by connecting the container onto a lock (,) fitted on the outside of the isolator (,) and equipped with a pulsed light sterilization device (,). The connection between the lock (,) and the isolator (,) is made by a sealed double door transfer device. The throwaway container is equipped with a plug type closer (,), cutout from the inside of the isolator (,) after sterilizing the volume (,) inside the lock (,) and opening the double door (,).

Process and device for transfer of sterile products between a container and an isolator

A tight transfer device (,) between two sterile volumes (,), of the double door or port type (,), is equipped with a decontamination system (,) using ultraviolet, pulsed ultraviolet or pulsed light radiation, of the facing points of the gaskets (,) ensuring the necessary sealing action. This decontamination system (,) is integrated into one (,) of the flanges of the transfer device. It comprises a collar (,) made from a material able to diffuse radiation, as well as optical fibers (,), whereof one end is mounted on said collar. The other end of the optical fibers (,) is connected to a radiation source. When the source is used, the radiation, routed by fibers (,) over the entire periphery of the collar (,), diffuse into the same towards the points of the gaskets (,) to be decontaminated.

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Villeromain, France

Jean-Michel Riviere