Sandoz Gmbh

Jean-Michel Bastian

Anton Ebnother

Richard Berthold

Fulvio Gadient

Erwin Waldvogel

Andre Stoll

Klaus Hasspacher

Michael Strasser

Erwin Rissi

Gustav Schwarb

The present invention provides anti-9,10-dihydro-4-(1-methyl-4-piperidylidene)-4H-benzo[4,5]-cyclohepta[1 ,2-b]thiophen-10(9H)-one oxime of formula ##STR1## useful for the treatment of allergic conditions.

Anti-allergic

This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, chlorine or lower alkyl,

Treating prostate hypertrophy with

The present invention provides compounds of formula, ##STR1## wherein n is from 0 to 4, m is from 0 to 4, whereby n+m is at least 1 and not more than 4, each of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 may independently be, for example, hydrogen, alkyl or alkoxy, R.sub.5 may, for example, be nitrile or carbamoyl and R.sub.6 is hydrogen and, when n is 2 and m is 0, one of R.sub.6 can be alkyl of 1 to 4 carbon atoms, which compounds possess pharmaceutical, for example antiallergic, activity.

Organic compounds

The present invention provides novel compounds of the formula, ##STR1## wherein R.sub.1 is hydrogen, halogen, alkyl or alkoxy; R.sub.2 may, for example, be hydrogen, alkyl, alkenyl, alkinyl or phenylalkyl, the phenyl ring of which may be mono-substituted with halogen, alkyl or alkoxy; and R.sub.3 is hydrogen, alkyl, thienyl, phenyl or phenyl which may be mono- or di-substituted with halogen, alkyl, alkoxy or alkylthio, useful, for example, as anti-depressants and analgesics.

Benz[g]isoquinolines and use thereof

The invention provides compounds of formula I, ##STR1## wherein each of R.sub.1 and R.sub.4, which may be the same or different, is hydrogen, halogen, alkyl or alkoxy; each of R.sub.2 and R.sub.3 is hydrogen, or together, oxygen; B and D together with the carbon atoms to which they are bound may be a benzene ring or a substituted or unsubstituted thiophene ring and A may, for example, be oxygen, sulpur, --CH.sub.2 --O--, --CH.sub.2 --S, ethylene or vinylene, useful as psychostimulants and vigilance-increasing agents.

1,4-Substituted piperazinyl derivatives useful as psychostimulants

This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, halogen of atomic number from 9 to 35 or lower alkyl,

This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, halogen of an atomic number from 9 to 35, or alkyl or alkoxy of 1 to 4 carbon atoms,

5-Substituted-1,2,3,4-tetrahydrobenzo[g]isoquinolines

The invention concerns novel compounds of the formula: ##STR1## wherein n is 1, 2 or 3 R.sub.1 is lower alkyl

Tricyclo piperidino ketones and soporific compositions thereof

Benzo cycloheptathiophene carboxylic acid derivatives

Novel benzo[5,6]cyclohepta[1,2-c]pyridines useful as anti-depressant and anti-cholinergic agents.

Benzo[5,6]cyclohepta[1,2-c]pyridines

This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, halogen of atomic number from 9 to 35, or alkyl or alkoxy of 1 to 4 carbon atoms,

4H-Benzo[4,5]cyclohepta[1,2-b]thiophenes

This invention provides new compounds of formula I, ##STR1## wherein N IS A WHOLE NUMBER FROM 1 TO 3,

This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, halogen of an atomic number of from 9 to 35, or alkyl of 1 to 4 carbon atoms,

This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen, alkyl or 1 to 4 carbon atoms, fluorine, chlorine or bromine,

The invention concerns novel indenopyridine derivatives of the formula: ##SPC1## Wherein m is 1, 2, 3 or 4, and

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Therwil, Switzerland

Jean-Michel Bastian