Sanofi Sa

Parcor

Jean-Marie Pereillo

Jean-Pierre Maffrand

Alain Bayol

Jacqueline Lansen

Eric Vallee

Francis Blanc

Jean P Maffrand

The present invention relates to novel xylan sulfates of average molecular weight comprised between 2000 and 5000 Daltons. The invention also relates to their process of preparation by fractionation and their use in therapeutics as orally active antithrombotic and hypolipaemic agents.

Xylan sulfates of low molecular weight, process for their preparation

This invention relates to new xylane sulfates having an apparent molar weight comprised between 7000 and 12000. This invention relates also to a process for their preparation by fractionation, and to the therapeutic application thereof as anti-thrombosis and hypolipemic agents.

Xylane sulfates, process for their preparation, and anti-thrombosis and

Piperazine compound of formula ##STR1## wherein R.sub. 1 is halogen, lower alkyl, lower alkoxy or trifluoromethyl, R.sub.2 and R.sub.3 form, together with the nitrogen atom to which they are attached a saturated heterocycle having n cyclic atoms, n being 4-8, have analgesic activity.

Piperazine compounds

2,3-Dihydrobenzofuran of formula: ##STR1## wherein R.sup.1 and R.sup.2 are each, independently, a lower alkyl or lower phenylalkyl or form, together with the nitrogen atom to which they are attached, a 4 to 8-membered saturated heterocyclic ring having 3 to 7 cyclic carbon atoms, a 4 to 8-membered saturated heterocyclic ring having 2 to 6 cyclic carbon atoms and two heteroatoms one of which is said nitrogen atom and the other is an oxygen atom, a sulphur atom or another nitrogen atom, said other nitrogen atom being optionally substituted by a phenyl, halophenyl, trifluromethylphenyl, lower alkylphenyl or lower alkoxyphenyl; n is 2 or 3, and the salts thereof.

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Toulouse, France

Jean-Marie Pereillo