Commissariat a L'energie Atomique Et Aux Energies Alternatives

Commissariat a L'energie Atomique

Jean-Marc Reymond

Philippe Mangeot

Sophie Kerhoas-Cavata

Raphael Boisgard

Annabelle Hamelin

The present invention relates to a male fluid coupling to be pushed into a female coupling in order to form a fluidic coupling device with no dead volume able to transfer a fluid, and to such a device. The female coupling () is coupled to a first pipe (C) communicating with a second pipe (C) passing through the male coupling, this female coupling having an internal push-fitting surface () ending in a female end () at which the first pipe emerges, and male coupling comprises an external push-fitting surface () ending in a male end () intended to lie inside the female coupling. This second pipe is pushed into the male coupling beyond the male end and has a free end () pressed fluid tightly against the female end by return means () which, during a push-fitting operation, collaborate with guiding and retaining means () designed to guide this second pipe as it slides through the male coupling while keeping this free end against the female end so as to eliminate any dead volume between the first pipe and the male coupling, making this male coupling compatible with all kinds of corresponding female couplings.

Multipurpose male fluidic coupling for a coupling device and device such as this incorporating it

A continuous automated extraction system and method for physically extracting at least one liquid phase of a series of liquid microsamples which are taken beforehand in discrete packets, both in space and in time, and are in stored is provided. The method may include an extraction system having a centrifuge provided with a plurality of microholders, at least one of which is filled with the corresponding microsample and includes a filling upper portion that is extended by a separating lower portion of smaller cross section than that of the upper portion. Each filled microholder has a mass which is more than ten times the mass of this microsample, in such a way that it is possible to extract, by centrifugation, at a given instant, only a single microsample contained in a single microholder, or several microsamples contained in some or all of these microholders, progressively as the latter are filled.

System and method for the continuous extraction of a liquid phase of microsamples, and automated installation for taking them, for carrying out the extraction and taking measurements

The invention relates to a fluid connection device and to a continuous automated system and method for taking fluid microsamples using this device. A device () according to the invention, which is intended to be connected to a first line () via a first opening and includes a second opening through which a second line () passes, comprises: According to the invention, this second line is formed from a flexible microtube pushed right through the male connector beyond the male end, the free end of the second line pressing in a sealed manner against the female end so as to minimize the dead volume between the first line and the male connector.

Fluid connection device, system and method for continuously taking fluid microsamples using this device

The invention relates to a device and a method for counting elementary particles emitted by a fluid, the device comprising a line for transferring the fluid and, outside the line, detection means () for detecting the particles that are attenuated by a wall of the line and/or by this fluid. A counting device according to the invention includes at least one counting portion () of oblong cross section which joins together two adjacent portions of the line having a larger flow section and which has an [internal height (h)/internal width (l)] ratio of 20% or less, in which the internal height and the internal width represent the smallest and largest transverse dimensions respectively of the portion, these being measured along two approximately perpendicular directions, said detection means extending transversely to this portion, facing its entire internal width and on either side thereof.

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Saint-Remy-les-Chevreuse, France

Jean-Marc Reymond