Optomak, Inc.

Jean-Luc Néron

Sead Doric

Harold Dehez

Olivier Dupont-Therrien

A multi-site fluorescence recording system provides simultaneous monitoring of cell activity in different brain regions of a freely moving animal. The system includes an electrical rotary joint that couples signals to and from an external data acquisition and control unit connected to a stator of the rotary joint, which releases twisting of the optical fibers connected to the animal. Electrical signals are coupled to one or more fluorescence stimulation/detection units on the rotor of the rotary joint. The fluorescence stimulation/detection units receive one or more connections from optical fibers that connect the stimulation/detection unit(s) to the different brain sites. The rotating stimulation/detection units include spectral filters to separate the excitation light from the fluorescence signal, light sensors (an image sensor or photodiodes) and excitation light sources.

Cable movement-isolated multi-channel fluorescence measurement system

A pumped fluorescent light source includes one or more mirrors that direct pumping light from one or more pump sources on a fluorescent body having a planar top surface and a convex back surface. The top surface may be coated with an anti-reflective coating and the back convex surface may be coated with a reflective coating to improve efficiency. The body top surface may also be roughened to scatter a portion of the excitation light provided from the mirror(s) to generate a white output beam. The mirror(s) have reflective surfaces disposed outside of a collection area of an output beam of the light sources, so that the collection area is not obstructed by the mirror(s). The light source also includes a collecting lens for collecting the light emitted by the body. The mirror may be a single parabolic mirror that focuses the excitation light on the body to stimulate emission.

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Jean-Luc Néron