Symetis Sa

Boston Scientific Corporation

Boston Scientific Scimed, Inc.

Boston Scientific Medical Device Limited

Jean-Luc Hefti

Stephane Delaloye

Luc Mantanus

Jacques Essinger

Fabien Lombardi

Youssef Biadillah

Serge Delaloye

Stéphane Delaloye

Pierre Simonin

Michael Paris

Lionel Flaction

Yutit Wanakoht

Reynald Passerini

A delivery catheter for a stent. The delivery catheter may have a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further includes a handle at its proximal end and at least one sheath which may at least partially circumferentially cover the stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on the handle portion. The catheter further includes at least one radio-opaque indicator for indicating a rotational orientation of the delivery catheter and/or the stent when observed using medical imaging during implantation of the stent.

Catheter delivery system for stent valve

Embodiments of the present disclosure are directed to stents, valved-stents, (e.g., single-stent-valves and double stent/valved-stent systems) and associated methods and systems for their delivery via minimally-invasive surgery. The stent component comprises a first stent section () a second stent section () a third stent section () and a fourth stent section ().

Stents, valved-stents and methods and systems for delivery thereof

Apparatus () for compressing a transcatheter cardiac stent-valve () comprises: a first compressor stage () including a hollow channel () with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage () comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.

Method and apparatus for compressing/loading stent-valves

Stent-valves (e.g., single-stent-valves and double-stent-valves) and associated methods and systems for their delivery via minimally-invasive surgery are provided. The stent-valves include a stent component having a first flared end region and a second end, a plurality of leaflets coupled to the stent, and a sealing element coupled to the first end region.

Stent-valves for valve replacement and associated methods and systems for surgery

A delivery catheter for a prosthetic heart valve, the valve expandable from a collapsed condition for delivery to an expanded condition for implantation, the delivery catheter comprising: a holder for engaging the valve in the collapsed state of the valve, the holder configured such that (i) in response to a radial compression force exerted thereon, the holder has a first shape defining an exposed engagement region for engaging at least a portion of the collapsed prosthetic heart valve for restraining axial displacement of the prosthetic valve in at least one axial direction of the catheter, and (ii) in response to removal of the radial compression force upon expansion of the valve, at least a portion of the holder transitions to a second shape.

Prosthetic valve. delivery apparatus and delivery method

A delivery catheter for a stent. The delivery catheter may comprise a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further comprises a handle at its proximal end and at least one sheath which may at least partially circumferentially cover said stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on said handle portion.

Apparatus () for compressing a transcatheter cardiac stent-valve () comprises: a hollow channel () having an interior surface () shaped for progressively compressing the stent-valve in response to longitudinal advancement of the stent-valve within the channel; a driver () threadedly engaged on the exterior of the channel for generating a longitudinal driving force in response to rotation; a mover () having limbs () that project through slots () in the channel wall to transmit the driving force to the stent-valve within the channel; and a channel extension () removably attachable at the exit () to provide a generally cylindrical containment bore ().

A delivery catheter () for a stent valve (), the delivery catheter having a distal portion () insertable into an anatomy, the distal portion comprising an accommodation region () for accommodating a stent-valve for delivery into the anatomy, the delivery catheter further comprising at least one sheath () that is translatable between a closed position for at least partly closing the accommodation region and an open position for at least partly opening the accommodation region.

Stent valve, delivery apparatus and method therefor

Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.

Transcatheter stent-valves and methods, systems and devices for addressing para-valve leakage

A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprises material that swells in response to contact with blood. In some embodiments, the seal comprises a flap or pocket that is distensible in response to backpressure and/or paravalve back-flow of blood.

Transcatheter stent-valves

A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.

Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device

A stent-valve having a valve component and a stent component for housing the valve component, as well as associated methods and systems for delivery of the stent-valve via minimally-invasive surgery. The stent-valve can be configurable between two or more configurations to assist in delivery of the stent-valve to an implantation site of a patient.

Growing community of inventors

Cheseaux-Noreaz, Switzerland

Jean-Luc Hefti