Centre National De La Recherche Scientifique

Institut Curie

Other

Institute Curie

Université Pierre Et Marie Curie

Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic

Sorbonne Université

Université Pierre Et Marie Curie (Paris 6)

Université De Paris

Etat Francais Represented by Ministere De La Defense

Fluigent Paris-Biotech-Faculte De Medecine

Cnrs-Dae

Sorbonne Universite, Centre National De La Recherche Scientifique

Centre National De La Recherche Scientifique-Cnrs

Viovy, Jean-Louis

Jean-Louis Viovy

Laurent Malaquin

Max Chabert

Stephanie Descroix

Bastien Venzac

Valessa Barbier

Kevin Dorfman

Olivier Braun

Jean-Michel Peyrin

Jacques Lewiner

Paul Mallo

Ulrich Bockelmann

Stefano Begolo

Jean Rossier

Ayako Yamada

Anais Ali Cherif

J&eacute;r&ocirc;me Bibette

Ismaïl Cisse

François Amblard

Claus Futterer

Lucile Alexandre

Nicolas Davis Minc

Jérémie Weber

Jan Sudor

Dominique Hourdet

Anaïs Ali Cherif

Pascal Mayer

Jacques Prost

Sandrine Miserere

Iago Pereiro

Renaud Renault

Sanae Tabnaoui

Ivan Ferrante

Stéphanie Descroix

Jean-Hugues Codarbox

Bernard Brugg

Jean-Baptiste Durand

Mohamed Lemine Diakite

Catherine Villard

Laure Saias

Armand Ajdari

Paul Gougis

Jeremie Weber

Maeva Vignes

Debjani Paul

Claude Houdayer

Dominique Stoppa-Lyonnet

The present invention relates to a microfluidic device to manipulate, select, treat, or cultivate living bodies, comprising a first chamber, a second chamber and a network of guiding tracks, wherein: said network of guiding tracks comprises at least one first guiding track connecting the first chamber and the second chamber and at least one second guiding track connecting said at least one first guiding track with at least two interconnections; and said at least one second guiding track comprises a curved part; said curved part exhibiting a concavity facing the second chamber or the part of the network connected to the second chamber.

Microfluidic device for controlling the geometry of living bodies

A microfluidic device for performing physical, chemical or biological treatment to at least one packet without contamination.

Device for manipulation of packets in micro-containers, in particular in microchannels

Disclosed is a minifluidic device including a matrix, an elongated guiding duct embedded at least in part in the matrix, with at least one port to the outside of the matrix, a movable fiber at least partly contained in the guiding duct, and able to undergo within the guiding duct, and at least along some part of the fiber, at least one action selected among a sliding, or a deformation, or a rotation and at least one of the movable fiber or the guiding duct is elastic or is non linear along at least part of its length, or at least part of the matrix is elastic.

Fluidic devices with at least one actionnable fiber

A device for cell culture, in particular of neuronal cells, including: a substrate defining a first microfluidic chamber to be seeded with a first cell culture, and at least a second microfluidic chamber, a fluidic interconnection system connecting the first and second chambers and enabling cellular extensions, in particular axons, to extend from one chamber to the other, wherein the interconnection system of the device is made so as to promote the progression of at least one first type of cellular extension, the first and second types of extension being different either due to the microfluidic chamber from which they originate, or due to the type of cell of which they constitute an extension.

Device for cell culture

The invention relates to a method for detecting organisms in a liquid sample, comprising the provision of a capture area including particles in a liquid medium and subjected to a hydrodynamic flow, wherein the organisms to be detected are capable of binding to these particles, the method comprising the steps of: The invention also relates to a system for implementing this method.

Method for detecting organisms in a diluted sample

Disclosed is a fluidic device including at least: a) a solid matrix; b) a textile component, embedded in the matrix and mechanically cohesive with the matrix; c) at least one channel embedded in the matrix and entangled with the textile component, the channel being at least partly open. A method for making a fluidic device includes providing a textile component including support fibers and at least a movable fiber entangled with the textile, embedding at least part of the textile and part of the movable fiber, in a matrix precursor material, applying a treatment in order to obtain a solid matrix.

Composite woven fluidic device

The present invention concerns a microfluidic system comprising: a microchannel containing several elements of two non-miscible fluids, the microchannel comprising a droplet () containing magnetic particles (M), and a device for generating inside the microchannel magnetic field, said device comprising an activable magnetic element, the activable magnetic element comprising a tip (), the microfluidic system being configured to transport the droplet by flow or by pressure difference.

Microfluidic system

The invention concerns a microfluidic system () comprising: The invention also concerns a method for treating a sample that can be implemented with this system.

Microfluidic system having a magnetic particle bed

The present invention concerns a method of detecting macroions in a liquid medium contained in a space, the method including: a) submitting the liquid medium to a stimulating electrical field to induce formation of aggregates of macroions, the formed aggregates of macroions preferably not including any additional labeling agent, and b) measuring, in a detection zone of the space, spatial and/or temporal fluctuations within the liquid medium of at least one variable depending on the concentration of the macroions in the liquid medium, and c) determining, based on these fluctuations, the presence of the macroions, step c) preferably including processing by a time-dependent or space dependent analysis, more preferably by wavelet analysis, or by autocorrelation the fluctuations measured at step b).

Method and devices for detecting macroions in a liquid medium

A straight, branched or cross-linked polymer, including, per 100 mol %: a) a mole fraction from 75% to 99.95% of monomer units from an N,N-dialkyl acrylamide; b) a mole fraction from 0.05% to 1% of monomer units from a monomer of formula (I): CH2=C(Ri)-C(&#x2550;O)&#x2014;O&#x2014;[(CH2-CH(R2)-O]n-R3 (I); c) optionally a mole fraction higher than 0% to 24% either of monomer units from a monomer including a free strong acid function, partially or totally salified, or of monomer units from a monomer of formula (II): CH2=C(R4)-C(&#x2550;O)&#x2014;Y&#x2014;(CH2)m-N(R5)(R6) (II); d) optionally a mole fraction higher than 0% to 1% of a diethylene or polyethylene cross-linking monomer. Also, a method for treating a surface made of a hydrophobic material, using the polymer, and an aqueous, hydro-organic or organic solution including the polymer for modifying interactions between the species contained the solution and the hydrophobic surface.

Amphiphilic polymers and use thereof in the treatment of surfaces made of hydrophobic materials

A method for encapsulating or sorting colloidal objects, comprising the step of flowing said objects in a first flow stream partly or fully surrounded by at least one second flow stream in a channel comprising a narrow strait, wherein along an elongated part of the path of said first flow stream either (a) the bidimensional size of said first flow stream is smaller than the largest bidimensional size of at least some of said objects, either (b) the smallest unidimensional size of said first flow stream is smaller than the largest unidimensional size of at least some of said objects, either (c) said first flow stream is splitting, in the absence of said objects, into droplets with a volume smaller than the volume of at least some of said objects, or (d) said first flow stream would have in the absence of said particles, a shape that cannot entirely encompass some of said objects.

Encapsulation microfluidic device

An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.

Non-thermosensitive medium for analyzing species in a channel and for minimizing adsorption and/or electroosomosic phenomena

The present invention concerns a microfluidic device () for performing physical, chemical or biological treatment to at least one packet without contamination.

Non-thermosensitive medium for analyzing species in a channel and for minimizing absorption and/or electroosomosic phenomena

Growing community of inventors

Paris, France

Jean-Louis Viovy