Synthelabo

Laboratoires Fournier Sa

Fournier Industrie Et Sante

Grelan Pharmaceutical Co., Ltd.

Laboratories Fournier S.a.

Laboratoires Fournier S.c.a.

Jean Louis Binet

Philippe Michel Manoury

Gerard Defosse

Elisabeth Dewitte

Martine Barth

Pierre Dodey

Olivia Poupardin-Olivier

Christiane Legendre

Soth Samreth

Daniel C Obitz

Benaïssa Boubia

Corinne Veronique

Daniel De Fornel

Benaiessa Boubia

Henry Najer

Don Pierre Giudicelli

Guy Rossey

Alexander E Wick

Icilio A Cavero

Patrice Renaut

Bogdan Iliesco-Branceni

Nagatoshi Wagatsuma

Michel Aletru

Hirotaka Kasai

Christian Guffroy

Najib Jabri

Thierry Boucher

Indole compounds corresponding to the formula (I): as defined in the claims, pharmaceutically acceptable addition salts of such compounds, pharmaceutical compositions containing such compounds, the process for their preparation, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular disease, inflammatory disease and neurodegeneration.

Method of treating conditions involving PPAR-receptors with indole compounds

Indole compounds, method of preparing them and uses thereof

A method of activating PPAR receptors in a subject, said method comprising administering to said subject an effective PPAR receptor activating amount of a pyrrolopyridine compound corresponding to formula (I): wherein R, R, R, R, R, X, Ar and n have defined meanings, or a pharmaceutically acceptable salt thereof, particularly as part of the treatment of a disorder or disease state selected from the group consisting of atherosclerosis, myocardial infarction, hypertension, and cerebral vascular disease.

Use of pyrrolopyridine compounds for activating PPAR receptors and treatment of conditions involving such receptors

Pyrrolopyridine compounds corresponding to formula (I): as defined in the claims, pharmaceutically acceptable salts thereof, the process for preparing such compounds, pharmaceutical compositions containing such compounds, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular diseases, inflammatory diseases and neurodegenerative diseases.

Pyrrolopyridine compounds, method of making them and uses thereof

2-ureido-benzamide derivatives

Derivatives of .beta., .beta.-dimethyl-4-piperidineethanamine as

1,2,3,5,6,7,8,8a-Octahydro-5,5,8a-trimethyl-

An indolone derivative is useful for the treatment of anxiety, depression and schizophrenia and is a 5HT.sub.1A agonist and 5HT.sub.2 antagonist, which is a compound of formula (I): ##STR1## in which R.sub.1 is a hydrogen or halogen atom or a (C.sub.1-4)alkyl radical,

Indolone derivatives, their preparation and their application in therapy

Phenyloxypropanolamine derivatives in the form of racemates or enantiometers, of formula (I) ##STR1## in which R is H or CH3, and their pharmaceutically acceptable salts.

Phenyloxypropanolamine derivatives and their application in therapeutics

A piperazine derivative of formula (I) ##STR1## in which: R is hydrogen or a straight or branched (C.sub.1 -.sub.4) alkoxycarbonyl group; and

Piperazine derivatives and their preparation process

Benzimidazole derivatives corresponding to the formula (I) ##STR1## in which X is CH or N,

2-[4-pyrimidin-2-yl amino)piperidin-1-yl]benzimidazole compound

A compound which is a benzimidazole derivative of formula (I) ##STR1## in which: R.sub.1 is hydrogen or methyl,

Antihistaminic benzimidazole derivatives

A compound which is a piperidine derivative of formula (I) ##STR1## in which: n is 1, 2, 3 or 4,

Piperidine derivatives, and their application in therapy

Benzimidazole derivatives corresponding to the formula (1) ##STR1## in which X is CH or N,

Benzimidazole derivatives and pharmaceutical compositions containing them

Imidazo[4,5-b]pyridin-2-one derivatives of the formula (I) ##STR1## in which n is 2, 3 or 4, x is .dbd.CH-- or .dbd.N--, R.sub.1 and R.sub.2, which may be the same or different, each represent hydrogen, halogen or (C.sub.1-4) alkoxy and either R.sub.3 is H or OH and R.sub.4 is H, or R.sub.3 and R.sub.4 together form a direct bond, their enantiomers and their addition salts with pharmaceutically acceptable acids are pharmacologically active, for example as antagonists to histamine and serotonin.

Imidazo[4,5-b]pyridin-2-one derivatives

Growing community of inventors

Ballainvillers, France

Jean Louis Binet