Adir Et Compagnie

Adir Et Cie

Adir, S.a.r.l.

Naturaceutic International Lvm Associes

Centre De Valorisation Des Glucides Et Produits Naturels

Jean Lepagnol

Georges Remond

Michel Vincent

Bernard Portevin

Yolande Herve

Gilbert Lavielle

Pierre Lestage

Alex Cordi

Patrice Desos

Guillaume De Nanteuil

Gilbert Regnier

Claude Guillonneau

Pierre Potier

Jean-Daniel Brion

Claude Thal

Jean-Gilles Parmentier

Luc Demuynck

Philippe Morain

Pascal Schmitt

Jean-Francedillaois Pujol

Pierre Renard

Michel Wierzbicki

Alain Dhainaut

Bernard Pirotte

Yves Rolland

Michael Spedding

Pascal De Tullio

Jacques Delarge

Bernard Serkiz

Bernard Masereel

Jean-Paul Tillement

Bernard Testa

Catherine Biton

Bernard Protevin

Veronique Heidet

Bhupesh Chandra Das

Christian Marazano

Delphine Compere

Gilbert Regnir

Arnaud Vannier-Moreau

Eric Prudhomme

Laura Barsotti

The invention relates to compounds of general formula (I):

Substituted tetrahydropyridin derivatives, method of preparation and pharmaceutical compositions containing them

A compound of formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3, which are identical or different, represent hydrogen, halogen, alkyl, nitro, cyano, aminosulfonyl, imidazolyl, or pyrrolyl, or alternatively, when two of them are situated on adjacent carbons, may form with the carbon atoms to which they are attached a benzene ring on C.sub.3 -C.sub.7 cyloalkyl

2-(1H) quinolinone compounds

Compound of formula (I): ##STR1## in which: R.sub.1, R.sub.2 and R.sub.3, which are identical or different, represent hydrogen or halogen or alkyl, nitro, cyano or aminosulfonyl, or alternatively, when two of them are located on adjacent carbons, form, with the carbon atoms to which they are attached, (C.sub.3 -C.sub.7) cycloalkyl ring or substituted or unsubstituted benzene ring,

2(1H)-quinolone compounds

A compound selected from those of general formula (I): ##STR1## wherein A represents a bivalent radical ##STR2## and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and Z are as defined in the description, the isomers and pharmaceutically-acceptable acid or base addition salts thereof, and medicinal products containing the same which are useful in the treatment of depression and anxiety.

Benzopyrrolizinoquinolizinones

A compound selected from those of general formula (I): ##STR1## wherein A represents a bivalent radical selected from ##STR2## and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and Z are as defined in the description,

EburnanE analogues

Compound of formula (I): ##STR1## in which R.sub.1, R.sub.2 and R.sub.3, which are identical or different, represent hydrogen or halogen or alkyl, nitro, cyano or aminosulfonyl, or alternatively, when two of them are located on adjacent carbons, form, with the carbon atoms to which they are attached, (C.sub.3 -C.sub.7) cycloalkyl ring or substituted or unsubstituted benzene ring,

A compound of formula (I): ##STR1## in the form of its S enantiomer, its addition salts with a pharmaceutically acceptable acid or base and medicinal product containing the same are useful for the treatment or prevention of pathologies associated with dysfunction of glutamatergic neurotransmission.

Benzothiadiazine compound

The invention relates to the compounds of formula (I): ##STR1## in which: A represents, with the carbon and nitrogen atoms to which it is attached, a heterocycle,

Bicyclic nitrogen compounds

The compounds are N-(unsubstituted or substituted) N'-benzylpiperazine compounds and pharmaceutically tolerable salts thereof, useful for treating neuronal disorders resulting from the dysfunctioning of oxidative metabolism. A compound disclosed is: N-ethyl N'-(2-hydroxy-3,4- dimethoxybenzyl)-piperazine and its dihydrochloride.

N-benzylpiperazine compounds

The invention relates to a compound selected from those of formula (I): ##STR1## in which A, R.sub.1, R.sub.2 and R.sub.4 are as defined in the description, and medicinal products containing the same which is useful for treating a pathology related to dysfunctioning of glutamatergic neurotransmission.

Pyridothiadiazines

The invention relates to the compounds of formula (I): ##STR1## in which: A represents, with the nitrogen and carbon atoms to which it is bound, a heterocycle,

Nitrogen-containing bicyclic compounds and pharmaceutical compositions

The invention relates to compounds of formula (I): ##STR1## in which: A represents, with the carbon and nitrogen atoms to which it is linked, cyclic amide as defined in the description,

Peptide compounds containing a cyclic amide structure

The invention relates to the compounds of formula (I): ##STR1## in which: R.sub.1 represents a linear or branched, lower or higher alkoxy group or a substituted or unsubstituted amino group,

Substituted amino acid compounds

The invention relates to the compounds of general formula (I): ##STR1## in which: A represents, with the carbon and nitrogen atoms to which it is linked, a cycloamide group,

New heterocyclic tripeptide compounds

Growing community of inventors

Chaudon, France

Jean Lepagnol