Université Paul Sabatier (Toulouse III)

Centre Hospitalier Universitaire De Toulouse

Invivogen

The Provost, Fellows, Foundation Scholars, and the Other Members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin

Invivogen Sas

Jean-Gerard Tiraby

Daniel Drocourt

Thierry Lioux

Kingston Mills

Eric Perouzel

Antoine Blancher

Nicolas Congy

Patrick Kelly

A method for determining the quantity of anti-HLA antibodies of a liquid medium containing antibodies.

Anti-HLA monoclonal chimeric immunoglobulin, method and kit implementing such a monoclonal chimeric immunoglobulin

A monoclonal chimeric immunoglobulin wherein the heavy chains and the light chains are human by nature in their constant parts, in particular, the heavy chain constant parts are chosen from the group formed of the heavy chain constant parts of an IgA, of an IgG or of an IgM and the light chain constant parts are chosen from the group formed of the kappa chains and the lambda chains, and the light chain and the heavy chain variable parts are chosen from the group formed of monoclonal antibodies specific to monomorphic epitopes of HLA class I antigens and monoclonal antibodies specific to monomorphic epitopes of HLA class II antigens. A process for standardization of the screening and for quantification of anti-HLA antibodies in a liquid medium is also described.

Anti-HLA monoclonal chimeric immunoglobulin, process and kit employing such a monoclonal chimeric immunoglobulin

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Toulouse, France

Jean-Gerard Tiraby