Monica Healthcare Limited

Ge Precision Healthcare LLC

Minoca Healthcare Limited

Jean-Francois Pieri

Barrie Robert Hayes-Gill

Steven Mitchell Falk

John Andrew Crowe

Carl William Barratt

David Keith James

Mohammad Mohammad Khair

David Nottingham University Medical School James

A method of sensing the heart rate and blood oxygen saturation of a maternal patient and a fetal patient can include obtaining maternal electrocardiogram (mECG) data and fetal electrocardiogram (fECG) data with a plurality of electrodes. The method can also include obtaining photosignal data with an optical sensor, the photosignal data including a maternal photosignal component and a fetal photosignal component. Additionally, the method can include applying mECG to the photosignal data to calculate maternal photoplesthograph (mPPG) data, applying the mPPG to the photosignal data to remove the maternal photosignal component from the photosignal data, and applying the fECG to remaining photosignal data to calculate fetal photoplesthograph (fPPG) data.

Multi-sensor patch

A multi-sensor patch for simultaneous abdominal monitoring of maternal and fetal physiological data includes a multi-layer flexible substrate with a center region and a plurality of electrode regions. A conductive layer of the flexile substrate provides an electrical connection between each of the plurality of electrode regions and the center region. A plurality of electrodes are formed into the flexible substrate. At least one mechanical motion sensor is connected to the multi-layer flexible substrate. A module unit is connected to the conductive layer at the center region. The module unit includes a controller configured to receive biopotential physiological data from the plurality of electrodes and mechanical sensor data from the at least one auxiliary sensor. The controller calculates at least fetal heart rate, maternal heart rate, and uterine activity from the biopotential physiological data and from the mechanical sensor data.

A multi-sensor patch for simultaneous abdominal monitoring of maternal and fetal physiological data includes a multi-layer flexible substrate. The multi-layer flexible substrate includes a center region and a plurality of electrode regions. An electrode of the plurality of electrodes is located in each of the electrode regions. At least one auxiliary sensor which may be an optical sensor. A module unit is connected to the conductive layer at the center region. The module unit is configured to receive biopotential physiological data from the plurality of electrodes and photosignal data from the optical sensor. The module unit calculates at least fetal heart rate (fHR), maternal heart rate (mHR), and uterine activity (UA) from the biopotential physiological data and fHR, mHR, and SpO2 from the photosignal data.

The invention concerns a multi-electrode patch for abdominal electrophysiological detection. The patch has a flexible substrate interconnecting multiple electrodes and a module unit for removably engaging with an electronic readout device for detecting a maternal and/or fetal electrophysiological signal from the electrodes. The module has a mechanical module unit for removable mechanical engagement with a housing of the readout device, and an electrical module unit for making an electrical connection from the electrodes to the readout device. Engaging the patch with the readout device comprises engaging both the mechanical module unit and the electrical module unit. The patch may be flexible in a manner that allows variation in the relative positioning between the electrodes. The patch and/or electronic readout device may comprise a security device for communication of an authentication code.

Apparatus and method for detecting an abdominal electrophysiological signal

An apparatus and method for detecting uterine activity uses cutaneous electrodes on the maternal abdomen to obtain electrophysiological signals that can be used to obtain fetal and maternal heart rate. The apparatus includes a first input for receiving electrical signals from the cutaneous electrodes and a second input for receiving movement signals indicative of a movement of the maternal body from a movement detector. A signal processor separates a uterine electromyogram signal from fetal and maternal heart rate signals and filters out motion artifacts from the electromyogram using the movement signals. An output presents electrohysterogram (EHG) data from the uterine electromyogram signal.

Monitoring uterine activity

The invention relates to large area electrodes suitable for use in a fetal heart rate monitoring systems. The electrode comprises: a cutaneous gel contact () for sensing fetal electrocardiogram signals from a human pregnant subject; an electrical conductor () electrically connected to the gel contact () so as to define a first electrical contact region; a connector () in electrical contact with the electrical conductor () for connection to a lead wire; and a substructure () for attachment to a human pregnant subject. The gel contact () and the electrical conductor () are arranged on the substructure () to allow a contact surface () of the gel contact () to be in electrical communication with the skin of a human pregnant subject to define a second electrical contact region. The second electrical contact region has an area greater than 370 square millimeters. When arranged on a predefined electrode topology on the abdomen the success rate of fetal heart rate detection is significantly improved. The topology may be incorporated into a flat flexible cable which provides a comfortable and reproducible electrode arrangement allowing an untrained person to apply electrodes to a pregnant mother's abdomen.

Electrode and electrode positioning arrangement for abdominal fetal electrocardiogram detection

Fetal behavior is monitored by receiving ECG data from a set of electrodes attached to a material body. A waveform pre-processor identifies a succession of fetal ECG complex waveforms within the received data and a waveform processor determines differences in the processor succession of fetal ECG complex waveforms over time. An event logger determines from the determined differences a number of fetal movements during the period of time. Fetal spatial presentation and/or position within the uterus may also be determined from fetal ECG data acquired from a plurality of electrodes positioned on the maternal abdomen in a predetermined configuration. A number of fetal ECG complex waveforms are identified within the data, and each of the waveforms is compared with a set of predetermined fetal ECG complex templates ascribed to the predetermined electrode configuration to determine a template that best matches the identified fetal ECG waveforms.

Fetal surveillance

The spatial position of a fetus within the womb is determined and monitored through analysis of ECG waveform data received from a set of electrodes that are attached to a maternal abdomen in a predetermined configuration. The waveform is compared with a set of predefined stored templates to determine the position of the fetus. An event logger may determine the number of fetal movements during a period of time.

The present invention relates to apparatus for detecting the heart rate of a fetus. The apparatus includes at least two detectors for detecting heart beats of the fetus, each detector comprising at least two electrodes for detecting ECG signals. A processor, which is coupled to the detectors, is used to process the ECG signals received from each detector and determine the heart rate of the fetus.

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Nottingham, United Kingdom

Jean-Francois Pieri