Commissariat a L'energie Atomique

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Stmicroelectronics (crolles 2) Sas

Université Joseph Fourier

Stmicroelectronics (rousset) Sas

Institut Polytechnique De Grenoble

Arjo Wiggins Fine Papers Limited

Avalun

Jean Berthier

Nicolas Posseme

Ivan-Christophe Robin

Florence Rivera

Sophie Le Vot

Patrick Pouteau

Fabien Sauter-Starace

Yves Fouillet

Serge Valette

Lea Di Cioccio

Marcel Locatelli

Olivier Raccurt

Myriam-Laure Cubizolles

Skandar Basrour

Léa Di Cioccio

Vincent Poher

Henri Glenat

Anne-Gaelle Bourdat

Séverine Cheramy

Naceur Belgacem

Maxime Huet

Johanna Spiaczka

Didier Chaussy

Sebastien Mermoz

Pascal Manet

Francis Robach

Arnaud Buhot

Sébastien Mermoz

Marjolaine Allain

Jerome Ventosa

David Gosselin

Gwenola Sabatte

Jérome Ventosa

Jean-Marie Baumlin

Gaël Georges Félix Depres

The invention concerns a support intended for the implementation of a method of self-assembly of at least one element on a surface of the support, including at least one assembly pad on said surface, a liquid drop having a static angle of contact on the assembly pad smaller than or equal to 15&#xb0;, and nanometer- or micrometer-range pillars on said surface around the pad, the liquid drop having a static angle of contact on the pillars greater than or equal to 150&#xb0;.

Process for manufacturing assembly pads on a carrier for the self-assembly of an electronic circuit on the carrier

A device for taking a sample of liquid by capillarity, including a channel for flow of the liquid delimited by two internal walls of the device between which a channel bottom extends, the distance separating the two internal walls decreasing in the direction of the channel bottom, the channel extending between a first collecting end, open onto outside of the device and configured to receive the liquid, and a second end, to enable the liquid to flow by capillarity along the channel bottom from the first end towards the second end. The channel includes, at the second end, a blocking structure to block the flow of liquid in the channel from the first end towards the second end.

Device for taking a liquid sample by capillarity and associated analysis method

A device for analyzing a biological sample which includes a separation and detection chamber into which an injection channel and a discharge channel open, a filter separating the chamber into two distinct spaces so as to define a first space into which the injection channel opens and a second space into which the discharge channel opens, the filter having a porosity suitable for the separation to be carried out, a rough bearing surface having a surface roughness parameter suitable for carrying out a mechanical lysis of the biological species present in the sample, the bearing surface being arranged in the first space, a flexible membrane arranged opposite the rough bearing surface relative to the filter and blocking an opening made through the housing.

Device for analyzing a biological sample

The invention relates to a method of sorting submillimetric particles entrained in a fluid flowing in an axial direction of a main channel, the particles being of density different from the density of the fluid, and the method being characterized in that it implements, in a first region of the main channel, focusing of the particles along a wall () of the main channel () by means of at least one focusing device (), and downstream from said region, collecting of particles in at least one sorting and take-off device () in communication with the main channel () via an opening such that the particles collected are selected by the take-off device as a function of the size of said particles, and in that said at least one sorting and take-off device is a recirculation chamber () in communication with the main channel () and presenting at least one recirculation zone () for concentrating the collected particles.

Method of sorting particles or particle clusters in a fluid flowing in a channel

A support is provided, including a reception zone in which the external envelope matches the shape of a plate configured to be placed on a droplet deposited at least in the reception zone in order to achieve capillary self-assembly of the plate and the support, and at least one pair of tracks that extend on the support from the reception zone and that have a lyophilic-type affinity with the droplet such that an overflow of the droplet beyond the reception zone is guided in the tracks, wherein the at least one pair of tracks includes a first track and a second track that do not have the same lyophilic-type degree of affinity with the droplet.

Support for capillary self-assembly with horizontal stabilisation, fabrication method and use

A microfluidic valve including a microchannel, a membrane arranged so as to seal off the microchannel and equipped with resistive units, characterized in that at least one face of the membrane includes at least one groove, and in that the resistive units are arranged in the groove and are capable, when an electric control current flows through them, of expanding sufficiently under the effect of the heat produced by the flow of the electric current to cause the rupture of at least one part of the membrane.

Single use microfluidic valve

A microfluidic device for controlled encapsulation of particles of sub-millimetric dimensions, or clusters of such particles, the device comprising: a first duct for delivering a first liquid phase containing particles for encapsulating in suspension; a second duct for conveying a flow of a second liquid phase that is immiscible with said first liquid phase; the first duct opening out into the second duct and forming a fluidic junction therewith; at least one microfluidic duct for discharging the first liquid phase flowing in said first duct and provided with a mouth located upstream from said junction and liable to be obstructed, at least in part, by a particle in suspension, thereby causing pressure to rise in the first duct. The invention also provides a microfluidic system including such a device, and a method of encapsulation based on using such a device.

Microfluidic device, system, and method for controlled encapsulation of particles or particle clusters

A method for pumping through an orifice of a first substrate, a first volume of liquid in contact with a first hydrophobic surface of said substrate, wherein a pressure variation between the first volume of liquid and a second volume of liquid, located in contact with said orifice and a second hydrophobic surface of said substrate, is achieved by electrowetting.

Electrowetting pumping device and application to electric activity measurements

A microfluidic system and method for sorting cell clusters, and for the continuous and automated encapsulation of the clusters, once sorted, in capsules of sizes suitable for those of these sorted clusters is provided. The microfluidic system comprises a substrate in which a microchannel array comprising a cell sorting unit is etched and around which a protective cover is bonded, and the sorting unit comprises deflection means capable of separating, during the flow thereof, relatively noncohesive cell clusters, each of size ranging from 20 &#x3bc;m to 500 &#x3bc;m and of 20 to 10 000 cells approximately, such as islets of Langerhans, at least two sorting microchannels arranged in parallel at the outlet of said unit being respectively designed so as to transport as many categories of sorted clusters continuously to a unit for encapsulation of the latter, also formed in said array.

Microfluidic system and method for sorting cell clusters and for the continuous encapsulation thereof following sorting thereof

The invention relates to a method for pumping through an orifice () of a first substrate (), a first volume of liquid () in contact with a first hydrophobic surface of said substrate, wherein a pressure variation between the first volume of liquid and a second volume of liquid ('), located in contact with said orifice and a second hydrophobic surface of said substrate, is achieved by electrowetting.

Electrowetting pumping device and use for measuring electrical activity

An actuation device with several positions includes a support, at least one flexible membrane attached to the support forming at least one closed containment with the support with volume filled with at least one first liquid in the form of one or several drops, and at least a second liquid, the first liquid and the second liquid being immiscible, and an electrical device to modulate the profile of the membrane by controlling the shape of at least one of the drops.

Actuating device having a flexible diaphragm controlled by electrowetting

A process is described to detect conducting objects buried in the ground by sending a series of electromagnetic pulses and the return signal. The signal characteristics stored in the database are sets of numerical data which each define characteristics of decreasing curves of the values of previously-received signals then, in a search phase, the numerical values of samples ranked 1, 2, . . . n are recorded, representing a real decreasing curve of a received signal. The average real decreasing curve is created by determination of the average value of the samples, each of which represents the average value of the values of the samples of the same rank. A value representing the difference between the set of characteristics of the real average decreasing curve and each of the sets with the same database characteristics is calculated. The smallest of the differences is compared with the threshold value. There is detection if at least one difference is less than the predetermined threshold, the object and its burying depth being defined as the object in the database which had the minimum difference value.

Process for electromagnetic detection of conducting objects

The porosity and permeability of a geological formation (2) are determined on the basis of an electrofiltering phenomenon by exploiting the existence of non-linear electrofiltering phenomena. One or two pressure generators (11 ) are used to propagate a pressure wave in the formation. Electrodes (14, 15) applied against the wall of the formation pick up the electric response of the formation. The detection of a resonance frequency or a phase shift corresponding to an extremum of the electric response of the formation makes it possible to calculate the porosity or permeability of the formation or find their values from charts.

Determination of the porosity and permeability of a geological formation

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Meylan, France

Jean Berthier