Cadila Healthcare Limited

Jayprakash Ajitsingh Parihar

Shriprakash Dhar Dwivedi

Ashok Prasad

Piyush Rajendra Sharma

Mukul Hariprasad Sharma

Sanjay Jagdish Desai

Brij Khera

Alpesh Pravinchandra Shah

Mahesh Laljibhai Rupapara

Alpeshkumar Pravinchandra Shah

Samir Rameshbhai Gajjar

The present invention relates to Brexpiprazole having a purity of about 99.5% or more by area percentage of HPLC, having total impurities not more than 0.5% relative to brexpiprazole as measured by area percentage of HPLC, and having less than 0.1% 1-(benzo[b]thiophen-4-yl)piperazine or a salt thereof relative to brexpiprazole by area percentage of HPLC. The present invention also provides a composition comprising brexpiprazole having 1-(benzo[b]thiophen-4-yl)-piperazine or a salt thereof in an amount less than about 0.1% relative to brexpiprazole by area percentage of HPLC and process for the preparation of brexpiprazole.

Process for the preparation of brexpiprazole and intermediates thereof

Dapagliflozin compounds and process for dapagliflozin preparation are described. Pharmaceutical compositions comprising dapagliflozin or solvates of dapagliflozin, for the treatment of diabetes are also described.

Process for the preparation of dapagliflozin

Stable crystalline Form II and stable crystalline Form III of ivabradine hydrochloride and processes for their preparation are disclosed.

Polymorphic forms of ivabradine hydrochloride

The present invention relates to stable crystalline Form I of lorcaserin hydrochloride of Formula (IA) and processes for its preparation. The invention also relates to processes for the preparation of lorcaserin and pharmaceutically acceptable salts, solvates and hydrates thereof.

Processes for the preparation of lorcaserin

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Gujarat, India

Jayprakash Ajitsingh Parihar