Jawaharlal Nehru Centre for Advanced Scientific Research

Other

The Secretary of State for Health

Secretary of State for Health and Social Care

Jayanta Haldar

Padma Akkapeddi

Goutham Belagula Manjunath

Chandradhish Ghosh

Yarlagadda Venkateswarlu

Venkateswarlu Yarlagadda

Divakara Siva Sathyanarayana Murthy Uppu

Geetika Dhanda

Akkapeddi Padma

Vancomycin conjugates of Formula I, its stereoisomers, prodrugs, pharmaceutically acceptable salts, and metal coordination complexes thereof is described in the present disclosure. Further, the present disclosure relates to pharmaceutical compositions comprising vancomycin conjugates, its stereoisomers, prodrugs, pharmaceutically 10 acceptable salts, metal coordination complex thereof with one or more other pharmaceutical compositions or an antibiotic. The present disclosure also describes a process of preparing said conjugates, its stereoisomers, prodrugs, pharmaceutically acceptable salts, and metal coordination complex thereof, and pharmaceutical compositions as described above. Furthermore, the present disclosure describes 15 compositions and methods of treating conditions and diseases that are mediated by bacteria. 

Glycopeptides conjugates and uses thereof

The present invention relates to compounds that are cationic vancomycin analogs and their compositions. Method of making the compounds and their use as medicament for the treatment of bacterial infection are also disclosed.

Cationic antibacterial composition

The present disclosure relates to the field of medicinal chemistry and more particularly to the development of antimicrobial compounds. The disclosure relates to the synthesis and characterization of compounds comprising aromatic radical or an aliphatic radical, an alkyl amine and amino acid moiety wherein said compounds exhibit antimicrobial activity against various drug-sensitive and drug-resistant pathogenic 10 microorganisms.

Antimicrobial compounds, their synthesis and applications thereof

The present disclosure relates to the development of antibacterial compounds and their nanoparticle compositions. Methods of making the compounds and their nanoparticle compositions, their use as medicament for the treatment of bacterial infection and also for suppressing potentially harmful inflammation are disclosed.

Nanoparticle compositions of antibacterial compounds and other uses thereof

Growing community of inventors

Bengaluru, India

Jayanta Haldar