Corteva Agriscience LLC

Dow Global Technolgoies LLC

Jayachandran Devaraj

Gregory T Whiteker

Noormohamed Mohamed Niyaz

Chunming Zhang

Jeremy Kister

Ronald B Leng

Rong Ling

Nicholas Martin Irvine

Abraham D Schuitman

Siyu Tu

Aaron A Shinkle

Nugzar Ghavtadze

Melissa Lee

Matthias Stefan Ober

Jossian Oppenheimer

Shawn D Feist

Michael Gullo

Mark E Ondari

Heqi Pan

Andre Yvon-Bessette

Amaruka Hazari

Patrick L Heider

Ian B Gillespie

Donnie W Blaylock

Rongrong [mandy] Lin

Will Kruper

Rongrong (Mandy) Lin

Methods for preparing a catalyst precursor material from dihalo-substituted metalloids are provided. The methods In include mixing a first solution of a halogenated alkane, at least one solvent, and a first component selected from a dihalo-substituted-group-14 metalloid or an organolithium reagent in a first reaction zone. Continuously adding the first solution to a second reaction zone, and continuously adding a second solution to the second reaction zone. The second solution including at least one solvent and a second component of either the dihalo-substituted-group-14 metalloid or the organolithium reagent, the second component is different from the first component. Mixing the first solution and the second solution in the second reaction zone.

Methods for preparing catalyst precursor materials

Methods for preparing 5-fluoro-6-(bromo or chloro)picloram analogs, or derivatives thereof, from picloram acid, picloram ester, or the nitrile analog of picloram are provided. The methods include chemical process steps that: (1) introduce a phthaloyl group onto the 4-amino substituent of picloram acid, picloram ester, or the nitrile analog of picloram, (2) add 2 fluorine atoms at the 5,6-positions of the pyridine ring using halex fluorination chemistry, (3) remove the phthaloyl group, hydrolyze the ester or nitrile substituent, and add chlorine or bromine to the 6-position by treatment with an acid and water, and finally, (4) esterify the 5-fluoro-6-(bromo or chloro)picloram acid produced in step (3) to a 5-fluoro-6-(bromo or chloro)picloram ester.

Preparation of halogen analogs of picloram

Improved methods for preparing chemical precursors to sulfonyl chloride III, which are important intermediates in the preparation of pyroxsulam herbicide are provided. Specifically, these precursors are compounds of Formulas VII and/or VIII, and IX, wherein R is a C-Calkyl, Ris a C-Calkyl, X is Cl or OH, Y is halogen, OH, or OR, and Ris a C-Calkyl. 

Preparation of sulfonamide herbicide process intermediates

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Zionsville, IN, United States of America

Jayachandran Devaraj