Invenio Imaging, Inc.

University of Michigan

Cytokinetics, Inc.

Aratome, LLC

Jay Trautman

Christian Freudiger

Larry C Mattheakis

Eugeni Vaisberg

Cynthia L Adams

Andrew Kelly

Jinhong Fan

Daniel Orringer

Aibing Rao

Gregg Peter Solar

David Lenzi

Gordon Wang

Balaji Pandian

Systems and methods are described for using a combination of high-resolution, optical-sectioning imaging modalities to provide quantitative measures of the distribution of a contrast agent in tissue samples by identifying its cellular distribution. In some instances, the systems and methods may be used in an intraoperative setting to guide a biopsy or surgical procedure.

Imaging system for detection of intraoperative contrast agents in tissue

Devices and systems for analyzing biological samples are provided. Devices include a hollow body extending from a first end to a second end. The body defines a sample collecting portion. A first opening at the first end of the body is operable to receive a source of negative pressure and a second opening at the second end of the body is operable to receive a biological sample. The body also includes an optically transparent region disposed in a region corresponding to the sample collecting portion, the optically transparent region being configured to transmit electromagnetic radiation therethrough from an imaging device capable of imaging the biological sample when disposed in the sample collecting portion.

Biopsy device for coherent Raman imaging

Disclosed herein are compositions, kits, methods, and systems for detecting a target molecule in a sample using a detection molecule.

Molecular detection using ligation amplification

Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, necrosis, cholestasis, and/or steatosis.

Predicting hepatotoxicity using cell based assays

Growing community of inventors

Los Altos, CA, United States of America

Jay Trautman