Schering Corporation

Jay A Waitz

Ann C Horan

Mahesh G Patel

Jay Weinstein

David J Cooper

Mae Counelis

Joseph A Marquez

Manohar G Kalyanpur

A new variety of Micromonospora carbonacea, namely Micromonospora carbonacea var africana NRRL 15099, ATCC 39149.

Micromonospora carbonacea var africana

The antibiotic 13-384 complex is elaborated by a new variety of Micromonospora carbonacea; namely Micromonospora carbonacea var africana NRRL 15099.

Antibiotic 13-384 complex from Micromonospora carbonacea var africana

The novel antibiotic complex designated hazymicin consisting of eight components, is produced by a novel strain of Micromonospora herein designated Micromonospora echinospora var. challisensis SCC 1411. Also disclosed are the structures of the two components namely, Component 5 and Component 6.

Broad spectrum antibiotic complex produced by a novel micromonospora

In the fermentation production of gentamicin C a plurality of additional antibiotic compounds are obtained. Four of these compounds, gentamicin A, gentamicin B, gentamicin B.sub.1 and gentamicin X exhibit significant anti-protozoal and anthelmintic activity while gentamicin B and B.sub.1 have significant antibacterial properties with markedly reduced side affects.

Amino glycoside antibiotics having antiprotozoal and anthelmintic

Actinomadura Kijaniata nov. sp produces a novel antibiotic which we have designated kijanimicin. The antibiotic or cationic salts thereof exhibit anti-acne, antitumor, antimalarial, antibacterial and anti-inflammatory activity.

Kijanimicin antibiotics and derivatives thereof

In the fermentation production of gentamicin C a plurality of additional antibiotic compounds are obtained. Four of these compounds, gentamicin A, gentamicin B, gentamicin B.sub.1 and gentamicin X exhibit significant anti-protozoal and anthelmintic activity while gentamicin B and B.sub.1 have significant antibacterial properties with markedly reduced side effects.

Growing community of inventors

Far Hills, NJ, United States of America

Jay A Waitz