Other

G & R Pharmaceuticals, LLC

Jay A Goldstein

Michael A Rothman

Whe-Yong Lo

A topical composition and the method using the composition, which contains an antifungal agent and a low potency anti-inflammatory steroid which is safe and effective such as desonide or its derivative. The low potency steroid agent does not cause side effects such as skin atrophy, striae and hypopigmentation. In a representative example, the low potency anti-inflammatory steroid has the following structure: wherein R, R, R, and Rtaken independently can be H, C1-C10 alkyl, C1-C10 alkenyl, C3-C10 cycloalkyl, and phenyl groups; Rand Rtaken together can be C3-C10 cycloalkyl; and R, and Rtaken independently can be H, C1-C10 alkyl, C1-C10 alkenyl, C3-C10 cycloalkyl, phenyl, C7-C10 phenylalkyl, carboxylate, sulfonyl, phosphoryl, and phosphonyl groups. The composition can be formulated in a dosage form such as a cream, ointment, gel, lotion, foam, powder, aerosol, spray, shampoo, or liquid solution. The composition can be used to treat a fungal disease such as tinea pedis, tinea capitis, tinea corporis, tinea versicolor, tinea cruris, and candidiasis as well as intertriginous dermatitis complicated by candidiasis.

Antifungal formulations

A sampling device and method for collection of sebum secreted by a person for determination of the person's skin oil characteristics includes a sampling element having a backing member of liquid impervious material. An absorbent material is disposed upon the backing member for absorbing sebum secreted by a person's skin, the absorbent material defining an absorption surface. A device is provided for disposing the absorption surface in contact with a region of the person's skin during the predetermined sampling period. The element is sealed within a liquid impervious pouch formed at least in part of the backing member during transport of the collected sebum to a site for measurement. A method for collection of sebum for selection of facial cosmetics of complementary formula is also described, including the step of providing a line of facial cosmetics formulated with oil and the like present at stepped levels preselected to complement a range of sebum production.

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Newton, MA, United States of America

Jay A Goldstein