Reheis, Inc.

Other

General Chemical Corporation

Jawahar Chunilal Parekh

Zijun Li

Pradip T Amin

Andrew M Rubino

Chung T Shin

Vijay Kumar Joshi

James Nelson Tanis

Rajanikant D Desai

A cost effective process is provided for making stable, efficacious, amino acid and polyhydric alcohol free concentrated aqueous aluminum zirconium salt solutions. Absence of amino acid, low iron content and low trace metal impurity levels improve compatibility with fragrances and minimizes the probability of the product color change and possibly fabric staining significantly. The novel aluminum zirconium actives also minimize iron contribution to underarm area that supports growth of microflora which is responsible for axillary malodour by the biotransformation of nonodorous precursors present in perspiration. The astringent complexes of the present invention may be obtained in solution or dry powder form. As a result, the complexes are satisfactory for use in any of wide variety of conventional antiperspirant forms.

Fragrance friendly and cost effective antiperspirant actives and method of making the same

An amino acid free stable aluminum zirconium polyhydric alcohol aqueous solution having a high anhydrous antiperspirant solid concentration and a high percentage of low molecular weight aluminum species, i.e., containing 60% or more of band IV peak area based on high pressure liquid chromatography, is prepared by adding a zirconium salt to an aqueous polyhydric alcohol solution of a basic aluminum chloride.

Amino acid free stable aluminum/zirconium antiperspirant solution

A stable aluminum-zirconium aqueous solution of enhanced efficacy having a high concentration free of amino acid and polyhydric alcohol is disclosed. Such aluminum-zirconium salts are selected from aluminum/zirconium tetrachlorohydrate; aluminum/zirconium pentachlorohydrate, and aluminum/zirconium octachlorohydrate in which the aluminum to zirconium (Al/Zr) atomic ratio of said salt falls within the limits of the shaded areas A, B, and C, respectively, of the drawing graph wherein the aluminum/zirconium tetrachlorohydrate has an Al/Zr atomic ratio from about 2 to about 6 and metal/chloride molecular ratio about 0.9 to about 1.25; aluminum/zirconium pentachlorohydrate having Al/Zr atomic ratio from about 6 to about 10 and metal/chloride atomic ratio from about 1.5 to about 1.65; and aluminum/zirconium octachlorohydrate having Al/Zr molecular ratio from about 6 to about 10 and metal/chloride molecular ratio from about 0.9 to about 1.5.

Stable aluminum/zirconium antiperspirant solution free of amino acid and polyhydric alcohol

Disclosed are aqueous antiperspirant active compositions comprising an admixtures of basic aluminum halides and a metal cation salts which yield enhanced antiperspirant efficacy; and methods of making such antiperspirant compositions. The basic aluminum halides, optionally contain an amino acid or salts of amino acids, and/or antimicrobial agent and are combined with a metal cation antiperspirant (e.g., Ti salt or Hf salt or Sn salt or Zr salt) and optionally with a organic solvent having at least two carbon atoms and at least one hydroxy group and mixtures thereof and methods of making such mixtures. Basic aluminum halides having enhanced antiperspirant efficacy are produced by reacting (a) aluminum powder; (b) an aluminum halide; and (c) water at a temperature greater than about 85&#xb0; C. This reaction is maintained until reaction products having an Al:halide ratio of about 1.2 to 1.5 and preferably 1.3 to 1.4:1; and a solution solids concentration of about 30-40 weight percent on an anhydrous basis are obtained. The basic aluminum halide of this invention are characterized as having a Size Exclusion Chromatography (HPLC) Test Band I of less than 5%, preferably less than 1%, Band II percent aluminum value of 20%-60% preferably about 35% to 55%, Band III percent aluminum value of 10% to 35% preferably 15%-30% and Band IV value of 15% to 50% preferably 25% to 35% and sum of peak 3 and 4 areas of at least 45% and no more than 70% and preferably 65%.

Enhanced efficacy basic aluminum halides/metal cation salt, antiperspirants actives and compositions containing such materials and methods for making

Disclosed are basic aluminum halides having enhanced antiperspirant efficacy; methods of making such materials and antiperspirant compositions containing such basic aluminum halides, and optionally an amino acid, salts of amino acids, antimicrobial agents, or an organic solvent having at least two carbon atoms and at least one hydroxy group and mixture thereof and methods of making such mixtures. Basic aluminum halides having enhanced antiperspirant efficacy are produced by reacting (a) aluminum powder; (b) an aluminum halide; and (c) water at a temperature greater than about 85&#xb0; C. This reaction is maintained until reaction products having an Al:halide ratio of about 1.2:1 to 1.5:1 and preferably 1.3 to 1.4:1; and a solution solids concentration of about 30-40 weight percent on an anhydrous basis are obtained. The products are characterized as having a Size Exclusion Chromatography (HPLC) Test Band I of less than 5%, preferably less than 1%, Band II percent aluminum value of 20-60% preferably about 35 to 55%, Band III percent aluminum value of 10 to 35% preferably 15-30% and Band IV value of 15 to 50% and preferably 25 to 35% and sum of peak 3 and 4 areas of at least 45% and no more than 70% and preferably 65%. The enhanced efficacy basic aluminum chloride salts of this invention are more economical to produce, show enhanced efficacy and are more stable compared to the conventional enhanced efficacy aluminum salts which show rapid degradation of Band III to Band II peak areas ratio are less irritant and more skin friendly.

Enhanced efficacy basic aluminum halides, antiperspirant active compositions and methods for making

Antiperspirant/deodorant active for no white residue sticks and soft solids

A halogen scavenging system is provided for inhibiting the corrosion-causing tendency and coloration of halogen-containing olefin polymers or copolymers, comprising incorporating about 0.01% to about 1% of a hydroltalcite-like solid solution having the formula Al (Mg) (OH) (CO ) (G) .eH O and a crystallite size in the <003> direction of about 190 &angst; to about 225 &angst;, and having bidentate coordination for carbonate ion as shown by an infrared spectrum, and wherein 3&lE;a&lE;5.5; 8&lE;b&lE;14; 1.2&lE;c&lE;3; 0&lE;d&lE;1; 1&lE;e&lE;10 and G is a surface active agent into the halogen containing olefin polymer.

Halogen scavenger for olefin formulations

An improved skin friendly antiperspirant is provided in which a suitable polyhydric alcohol e.g., glycerin, is complexed with the antiperspirant of the type of activated or nonactivated aluminum or aluminum/zirconium salt that are commonly considered antiperspirant active materials and are covered by FDA OTC Tentative Final Monograph as Category I. Suitable antiperspirant salts include (but are not limited to): aluminum chlorohydrate, aluminum sesquichlorohydrate, aluminum chlorohydrex PG, aluminum dichlorohydrex PG, aluminum sesquichlorohydrex PG, aluminum chlorohydrex PEG, aluminum sesquichlorohydrex PEG, aluminum chloride (15 percent or less aqueous solutions), aluminum zirconium chlorohydrates, aluminum zirconium trichlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium pentachlorohydrate, aluminum zirconium octachlorohydrate, aluminum zirconium trichlorohydrex Gly, aluminum zirconium penta chlorohydrex Gly, aluminum zirconium tetrachlorohydrex Gly, aluminum zirconium octachlorohydrex Gly, buffered aluminum sulfate, basic aluminum chlorides, zirconium hydroxychloride, zirconyl chloride, basic aluminum nitrates, basic aluminum chlorides combined with zirconyl oxychloride and/or hydroxychloride and organic complexes of each of basic aluminum chlorides with or without zirconyl chloride or zirconium hydroxychloride and mixture of any of the foregoing. Aluminum, zinc or zinc and zirconium complexes or aluminum, zinc and zirconium complexes with having metals/anion ratio of 0.9:1 to 2:1 where the anion is Cl, Br, I and/or NO, with or without additives such as amino acids or polyhydric alcohols.

Skin friendly antiperspirant composition and method of making

Stable aluminum-zirconium antiperspirant compositions in polyhydric alcohol solution with enhanced efficacy were made by direct reaction in aqueous solution of a soluble aluminum salt, a zirconium compound, a polyhydric alcohol, aluminum metal and optionally an amino acid buffer, and maintaining the solution at 100-140&deg; C. to form a 20-45% by weight concentration of aluminum-zirconium complexes on an anhydrous basis. A solid product can be obtained by spray drying the product solution.

Enhanced efficacy aluminum-zirconium antiperspirants and methods for making

Stable suspensions can be made from acidic metal salt solutions and finely divided acid-insoluble solid particles that have a particle size of less than twenty-five microns, preferably less than ten microns, and most preferably, about one micron. These suspensions can be used to treat surface waters to remove organic materials therefrom. The suspension forms a floc that includes the solid particles and organic materials, which floc rapidly settles out of solution, leaving purified water as the supernatant liquid.

Stable suspensions of solids in metal salt solutions for use in water

The formation of toxic compounds such as acetaldehyde and monochlorofluoroethane generated by aerosol antiperspirant mixtures of ACH and 1,1-difluoroethane can be substantially reduced by the addition of one or more additives. Such additives include amino acids, their alkali metal, alkaline earth, ammonium and hydroxy aluminum salts, metal glycinates, hydrotalcite or analogues thereof, and complex aluminum buffering agents. The resultant mixtures are stable for at least two years under ambient storage conditions.

Antiperspirant compositions for aerosol formulations

Basic aluminum halides and nitrates having enhanced antiperspirant efficacy are produced by reacting (a) aluminum powder, (b) an aluminum halide or nitrate solution and (c) water at a temperature greater than about 85.degree. C. This reaction is maintained until reaction products having an Al:anion ratio of about 1.2 to 1.8 and a solution solids concentration of about 30-40 wt. % on an anhydrous basis are obtained. The products are characterized as having a Size Exclusion Chromatography Test Band having a relative retention time corresponding to Band II of a Standard Basic Aluminum Chloride Size Exclusion Chromatogram and a Band II percent aluminum value of at least about 50% and a Band III percent aluminum value of less than 20%.

Method of inhibiting perspiration with basic aluminum and

Basic aluminum and aluminum/zirconium antiperspirants and method of

Processes are provided for preparing basic aluminum compounds of Formula I:

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Livingston, NJ, United States of America

Jawahar Chunilal Parekh