Fraunhofer-gesellschaft Zur Foerderung Der Angewandten Forschung E.v.

Javier Portillo

Jörg Kubusch

Jessy Schönfelder

Frank-Holm Rögner

Sebastian Ulbert

Martin Thoma

Klaus Fischer

Jana Burkhardt

The present invention relates to a method for irradiating a population of mammalian cells comprising at least one target mammalian cell with electron beams and/or X-rays, characterized in that: (i) a composition comprising a population of mammalian cells is irradiated in vitro with electron beams and/or X-rays, the population of mammalian cells containing at least one target mammalian cell and the dose rate being within the range from 5 Gy/sec to 10Gy/sec, and (ii) optionally viable target mammalian cells are isolated or enriched from the population of mammalian cells, and to agents obtainable thereby and to uses thereof.

Method for irradiating mammalian cells with electron beams and/or X-rays

The invention relates to the processing of fluid biological media, especially of culture media or cell- or virus suspensions, potentially containing active pathogens, with the aim of inactivating these pathogens and/or modifying ingredients in these biological media by thermal or radiological treatment.

Inactivation of pathogens in biological media

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Dresden, Germany

Javier Portillo