Psomagen, Inc.

Javier Gimpel

Jessica Richman

Zachary Apte

Daniel Almonacid

Rodrigo Ortiz

Eduardo Morales

Melissa Alegria

Valeria Marquez

Ingrid Araya

Luis Fernando Gomez

Mario Saavedra

Janyra Espinoza

Paulo Covarrubias

Janet Torres

Therapeutic compositions and an associated method for improving a Toll-like receptor (TLR)-related condition, including determining a set of peptide sequences associated with a microorganism-related modulator of a TLR, determining a first set of binding parameters for the set of peptide sequences in relation to the TLR, selecting a target subset of peptide sequences from the set of peptide sequences based on the first set of binding parameters, reengineering the target subset of peptide sequences based on mutating amino acid residues of the target subset of peptide sequences, determining a second set of binding parameters for the reengineered target subset of peptide sequences in relation to the TLR, and identifying a first peptide for use in a therapeutic composition for improving the TLR-related condition, based on the second set of binding parameters for the reengineered target subset of peptide sequences.

Therapeutic and diagnostics compositions targeting toll-like receptors and methods thereof

Embodiments of a method and/or system can include administering, to a patient with one or more conditions associated with at least one of TMA, TMAO, and/or derivatives thereof, a therapeutically effective amount of a compound for affecting inhibiting one or more CutC enzymes and/or CntA enzymes associated with microorganisms from at least one taxon from a set of microorganism taxa.

Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide

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San Franscisco, CA, United States of America

Javier Gimpel