Hansen Pharmaceutical, LLC

Jason R Hanft

Jeffrey L Jensen

Steve Jensen

Daniel Robert Jensen

Adam Scott Landsman

Embodiments of the present disclosure provide systems and devices for delivering gaseous Nitric Oxide (gNO) under therapeutic parameters to reduce infection in a subject. Certain embodiments include devices and systems for delivering pressurized gNO to reduce bioburden and promote healing in the wounds of subjects having various disease conditions, including skin and soft tissue infections (SSTIs) and osteomyelitis. In some embodiments, the present disclosure provides portable wound healing devices for delivering pressurized gNO to the site of a wound to treat various disease conditions in a subject. Other embodiments relate to systems and devices for delivering and for monitoring gaseous Nitric Oxide (gNO) under therapeutic parameters of use to treat a subject. In certain embodiment, the devices include a subject interface unit comprising sensors for detecting gNO pressure and/or gNO flow.

Gaseous nitric oxide delivery system and methods of use

Headgear includes a base configured to engage the head of the wearer. A force absorbing structure is carried by the base. In some cases, the force absorbing structure includes a surface including a coarse macrostructure configured to facilitate absorbing forces applied to the headgear. The coarse macrostructure includes a plurality of protrusions, and at least one of the protrusions has a thickness of at least about 0.50 mm. In some cases, the force absorbing structure includes a porous macrostructure configured to facilitate absorbing forces applied to the headgear. The porous macrostructure includes a plurality of passageways each having a width of at least about 2.00 mm.

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Coral Gables, FL, United States of America

Jason R Hanft