University of California

Lin Bioscience Pty Ltd.

Jason Olejniczak

Cheng-Chi Irene Wang

Jessica Crisp

Richard Truong

Tom Lin

Adah Almutairi

Yu-Hsin Tom Lin

Minnie Chan

Provided herein are compounds, pharmaceutical compositions, and methods of treatment for various diseases or conditions, such as cancer. In one aspect, the method comprises the treatment of metastatic cancers. Compounds and methods provided herein are also used for the treatment of diseases such as inflammatory disease, cardiovascular disease, autoimmune disease, and dry eye syndrome. Further provided herein are dietary supplement formulations and methods for supporting a healthy lifestyle.

Fatty acid analogues and methods of use

Provided herein are compounds, pharmaceutical compositions, and methods of treatment for various diseases, such as cancer. In one aspect, the method comprises the treatment of brain cancers or metastatic cancers that spread to the brain.

Tubulin inhibitors

PLGA-based polymers include pendant nucleophiles protected with photocleavable protecting groups. Upon deprotection, the polymers degrade rapidly via intramolecular cyclization into small molecules. The polymer may be formulated as a nanoparticle, with an encapsulated payload, which may be an imaging agent, a bioactive agent or a pharmaceutical agent.

Stimulus-responsive poly(lactic-co-glycolic)-based polymers and nanoparticles formed therefrom

Growing community of inventors

San Diego, CA, United States of America

Jason Olejniczak