Gilead Sciences, Inc.

Jason K Perry

Kevin S Currie

Peter A Blomgren

Jeffrey E Kropf

Zhongdong Zhao

Leena Patel

Christopher T Clark

Kirk L Stevens

Jayaraman Chandrasekhar

Yasamin Moazami

Nicole Nava

Natalie Seeger

Taryn Campbell

Jennifer Anne Treiberg

Suet Chung Yeung

Julian Andrew Codelli

Stephane Perreault

Kassandra F Sedillo

Julian A Codelli

Suet C Yeung

Richard L Mackman

Scott D Schroeder

James Ming Chen

Eda Y Canales

Devan Naduthambi

Oliver L Saunders

Michael R Mish

Gregory F Chin

Joshua J Van Veldhuizen

Stephen E Ammann

Alan X Huang

Weng K Chang

Henok H Kinfe

Christopher J Swank

Jessica L McKinley

Xinpei Cai

Kevin X Rodriguez

Choung U Kim

Scott E Lazerwith

Kuei-Ying Lin

David A Oare

Jay P Parrish

Sundaramoorthi Swaminathan

Lijun Zhang

Constantine G Boojamra

David Sperandio

The present disclosure relates to compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

Sars-cov2 main protease inhibitors

SARS-COV2 main protease inhibitors

The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.

Quinoline derivatives

The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), therapeutic methods for treating inflammatory disease.

Compounds for inhibition of &#x3b1;4 &#x3b2;7 integrin

Compounds for inhibition of alpha 4 beta 7 integrin

Compounds for inhibition of &#x3b1;4&#x3b2;7 integrin

Imidazopyridine derivatives

The invention provides unsaturated phosphonates of Formula I or a tautomer or pharmaceutically acceptable salt thereof, as described herein, as well as pharmaceutical compositions comprising the compounds, and therapeutic methods comprising administering the compounds. The compounds have anti-viral properties and are useful for treating viral infections (e.g. HCV) in animals (e.g. humans). 

Nucleoside analogs for antiviral treatment

A compound of Formula I, Formula II, Formula III, or Formula IV: or a pharmaceutically acceptable salt, solvate, and/or ester thereof, therapeutic compositions containing such compounds, and therapeutic methods that include the administration of such compounds.

Phosphonate inhibitors of HCV

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San Francisco, CA, United States of America

Jason K Perry