Senorx, Inc.

Medtronic Minimed, Inc.

Johnson & Johnson Surgical Vision, Inc.

Fusion Medical Technologies, Inc.

Alcon, Inc.

Alcon Research, Ltd.

Abbott Medical Optics Inc.

Jason H Safabash

Paul Lubock

Martin Victor Shabaz

Richard L Quick

Frank R Louw

Susan McConnell

April A Marano

Hans Lickliter

Jeffrey F Field

Randy W Adair

Kevin Springer

Lawrence C Kiliszewski

David W Gaylord

Randa M Bobroff

Jeffery Van Funderburk

John Merritt

Frederick Charles Houghton

Steven Thomas Charles

Glenn R Sussman

Jack Robert Auld

Rudolph F Zacher

Christopher L McCollam

Susan M McConnell

Jeffery V Funderbunk

Christopher S Dauer

Frederick C Hougton

Kevin R Springer

Laurence Kiliszewki

This intraocular lens (IOL) injector cartridge has a proximal opening in a main body for receiving an IOL. The main body has a lumen that extends longitudinally to a distal end having an opening smaller than the IOL. Passage through the lumen compresses or rolls the IOL so that when the distal end is inserted through a small incision in the eye the IOL can be expelled into the capsular bag. The distal end of the cartridge is beveled with a leading tip in front of a trailing heel. The characteristics of the beveled end are such that damage to the IOL is reduced. The bevel may be straight or curved and includes a distal face defined by the thickness of the distal end between the lumen and an exterior surface. The distal face may be flush with the bevel or chamfered. An inner corner angle between the distal face and the lumen is ≥60° to reduce the chance of scratching the IOL as it passes out of the distal opening.

Atraumatic IOL insertion cartridge opening

This intraocular lens (IOL) injector cartridge has a proximal opening in a main body for receiving an IOL. The main body has a lumen that extends longitudinally to a distal end having an opening smaller than the IOL. Passage through the lumen compresses or rolls the IOL so that when the distal end is inserted through a small incision in the eye the IOL can be expelled into the capsular bag. The distal end of the cartridge is beveled with a leading tip in front of a trailing heel. The characteristics of the beveled end are such that damage to the IOL is reduced. The bevel may be straight or curved and includes a distal face defined by the thickness of the distal end between the lumen and an exterior surface. The distal face may be flush with the bevel or chamfered. An inner corner angle between the distal face and the lumen is &#x2265;60&#xb0; to reduce the chance of scratching the IOL as it passes out of the distal opening.

A biopsy device includes a disposable elongated probe component having a coaxial arrangement of an elongated tubular section and an elongated tissue cutting member, and having a coaxial arrangement of a first driven gear, a second driven gear, and a third driven gear. The first driven gear is configured to rotate the elongated tubular section. The second driven gear is configured to rotate to longitudinally move the elongated tissue cutting member. The third driven gear is configured to rotate or oscillate the elongated tissue cutting member. A driver component has a coaxial arrangement of a first drive gear, a second drive gear, and a third drive gear. The first drive gear is drivably engaged with the first driven gear. The second drive gear is drivably engaged with the second driven gear. The third drive gear is drivably engaged with the third driven gear.

Biopsy device with selectable tissue receiving aperature orientation and site illumination

A biopsy device includes a cannula and a specimen collector. The cannula has a proximal end and a longitudinal axis. The specimen collector contains the proximal end of the cannula. The specimen collector has a removable sample receiving cartridge that is removable along the longitudinal axis of the cannula to expose the proximal end of the cannula.

Biopsy device with a removable sample recieving cartridge

An intraocular lens system may include a base that may include an annular body, an opening extending through the annular body in an axial direction of the annular body, and a recess extending circumferentially about the opening. The system also may include a lens that may be insertable into and removable from the recess. The lens may include a central optic, a first tab protruding radially away from the central optic, and a second tab protruding radially away from the central optic. The second tab may be more resistant to compression in a radial direction than the first tab. The first tab may include a first arm protruding radially away from the central optic, a second arm protruding radially away from the central optic and extending away from the first arm, and a third arm extending from the first arm to the second arm. Movement of one or more of the first, second, and third arms may result in deformation of the first tab.

Injector, intraocular lens system, and related methods

A biopsy device includes an elongated probe having a central longitudinal axis, a proximal end, and a distal end. A tissue penetrating tip includes a proximal base and a sharp distal point. The proximal base is secured to the distal end of the elongated probe. The sharp distal point is distal to the proximal base and is aligned with the central longitudinal axis. The tissue penetrating tip has a plurality of concave surfaces annularly arranged to form at least three adjacent pairs of concave surfaces. Each concave surface of the plurality of concave surfaces extends from the proximal base to the sharp distal point. Each adjacent pair of concave surfaces intersect to form a concave curved cutting edge. Cumulatively, the at least three adjacent pairs of concave surfaces form a plurality of concave curved cutting edges that distally terminate at the sharp distal point.

Biopsy device with aperture orientation and improved tip

An apparatus for collecting one or more tissue specimens includes a tissue specimen collector having a cannula receiving opening, a vacuum opening, and an interior. The vacuum opening is on a first axis, and the cannula receiving opening is on a second axis. A removable tissue specimen retaining member is positioned within the interior of the tissue specimen collector. The removable tissue specimen retaining member has a plurality of openings that are interposed between the first axis of the vacuum opening and the second axis of the cannula receiving opening. The removable tissue specimen retaining member is movable along the second axis. An elongated tissue cutting member extends through the cannula receiving opening of the tissue specimen collector to position a proximal end of the elongated cutting member in the interior above the plurality of openings of the removable tissue specimen retaining member.

Biopsy device with fluid delivery to tissue specimens

A method for collecting a tissue specimen from a target site within a patient includes rotating an elongated tubular section about a longitudinal axis to provide a desired aperture orientation of a tissue receiving aperture; applying a vacuum within the elongated tubular section to draw tissue at the tissue site through the tissue receiving aperture of the elongated tubular section into the interior thereof; advancing an elongated tissue cutting member longitudinally within the elongated tubular section to cut a tissue specimen from the tissue extending into the elongated tubular section; and applying a vacuum to the proximal end of the elongated tissue cutting member for transporting a cut tissue specimen through the inner lumen of the elongated tissue cutting member to discharge the cut tissue specimen directly from the proximal end of the elongated tissue cutting member into a tissue collection device.

The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.

Biopsy device with selectable tissue receiving aperture orientation and site illumination

A biopsy device includes an elongated probe having a central longitudinal axis, a proximal end, a distal end, and an aperture. A tissue penetrating tip includes a proximal base secured to the distal end of the probe. A sharp distal point distal to the proximal base lies on the central longitudinal axis. Each of a first, second and third concave surface is configured to extend from the base to the sharp distal point. The second concave surface is located to intersect the first concave surface to form a first curved cutting edge. A third concave surface is located to intersect the first concave surface to form a second curved cutting edge and is located to intersect the second concave surface to form a third curved cutting edge. Each curved cutting edge extends from the base to the sharp distal point. A tissue cutting device is coaxial with the probe.

A method of collecting one or more tissue specimens in a tissue biopsy system includes: providing a housing with a releasable proximal housing portion having an input port, a vacuum port, an interior, and a tissue specimen retaining member within the interior interposed between the input port and the vacuum port, the interior being in fluid communication with the inner lumen of an elongated tissue cutter, the tissue specimen retaining member having a plurality of openings configured to retain the one or more tissue specimens and to pass fluid and debris; inserting the proximal end of the elongated cutting member through the input port of the releasable proximal housing portion to position the proximal end in the interior above the plurality of openings of the tissue specimen retaining member; applying a vacuum to the vacuum port; and cutting a tissue specimen from a tissue site with the elongated tissue cutter.

Method of collecting one or more tissue specimens

This intraocular lens (IOL) injector for delivering an IOL into an eye of a patient includes an IOL load chamber and connected delivery tube, and a spring-loaded push rod for urging the IOL through the delivery tube and out of a distal tip thereof. The injector includes an actuator that is cocked to compress an automatic delivery coil spring. Cocking the actuator also folds the IOL and may elongate a dual optic IOL. A braking mechanism may be provided to permit control of the spring-biased IOL advancement. The injector is in a pen style with finger plates on the side for better ergonomic control.

Automated preloaded intraocular lens injector

The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component which is releasably secured to the driver component. The probe component has an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The driver has drive members for operating the elements of the probe component. The tissue penetrating distal tip preferably has a triple concave curvature shape with three curved cutting edges leading to a sharp distal point.

Growing community of inventors

Aliso Viejo, CA, United States of America

Jason H Safabash