Boston University

Photon-x, Inc.

Lucidux, LLC

Afferent Corporation

Jason D Harry

James B Niemi

James Joseph Collins

Stephen J Kleshinski

Attila A Priplata

Dirk Ahlgrim

Scott C Kellogg

Blair Allen Barbour

David Scott Ackerson

Francois I Luks

Gregg Draudt

Susan D'Andrea

Atilla A Priplata

A method and wearable system and for enhancing human balance and gait and preventing foot injury through neurological stimulation of the foot and the ankle. Subthreshold stimulation for neurosensory enhancement is provided via electrodes or vibrational actuators, or combination thereof, disposed in or on a wearable a platform, such as an insole, sock shoe, removable shoe insert, or applied without the support of a platform, to the skin surface of an individual. Suprathreshold stimulation for therapeutic purposes, such as improving blood flow, is also provided by the vibrational actuators. The actuators and electrodes are driven by bias signals generated by a bias signal generator that is coupled to a controller. The signal generator under the control of the controller is adapted to generate a non-deterministic random signal, a repetitive pattern or series of patterns. The controller optionally includes a communication port for interfacing with an external computer for purposes of optimizing and programming the controller. The wearable system is powered by a power source.

Method and apparatus for improving human balance and gait and preventing foot injury

Systems and methods deform the surface of the material with a probe, such as a mechanical device or a gas/liquid jet, while optically recording in detail the three-dimensional (3D) topography of the resulting surface deformation. The probe effectively applies a forcing function to the material, the attributes of which are known by performing calibrations prior to use or by direct measurement while it is applied. The topography is effectively the system output that is measured as indicative of the underlying mechanical properties of the material. In one application, systems and methods that apply a pressure in-vivo to human tissue and analyze a three-dimensional topography of the resulting surface deformation to identify localized inhomogeneities and anomalies in the human tissue.

Systems and methods for measuring mechanical properties of deformable materials

A neuro-stimulation system employs a includes a stimulator which may include electrode devices and/or vibration elements. A controller may be employed to drive the stimulating elements with an electrical signal. In response to the electrical signal, the stimulating elements deliver electrical and/or mechanical stimulation to the body part. The stimulation may be an aperiodic stimulation and/or may be a subthreshold stimulation. In one embodiment, the stimulator is disposable and the processor determines usage of the stimulator and ensures that the stimulator is limited to a certain amount of use. Neuro-stimulation systems may be applied to sensory cells of body parts during movement of the body parts to induce neuroplastic changes. Such movement may involve a variety of therapeutic applications, e.g. in stroke patient therapy.

System and method for neuro-stimulation

The invention features methods and apparatus for enhancing neurophysiologic performance, such as sensorimotor control and neuroplasticity. A preferred method involves inputting bias signals to sensory cells of a subject, thereby improving sensory cell function, while the subject is performing a predefined physical activity. A system used to practice the method of the invention includes a wearable device to which is secured at least one repositionable signal input device and a signal generator that is communicatively coupled to the signal input devices.

Method and apparatus for neurophysiologic performance

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Rumford, RI, United States of America

Jason D Harry