Ptc Therapeutics, Inc.

Pct Therapeutics, Inc.

Jason D Graci

Zhengxian Gu

Young-Choon Moon

Neil Gregory Almstead

Jeffrey Allen Campbell

Soongyu Choi

Hongyan Qi

Liangxian Cao

Marla L Weetall

Peter Seongwoo Hwang

Langdon Miller

William Jospeh Lennox

Thomas W Davis

Christopher Robert Trotta

Donald Thomas Corson

Harry H Miao

Tamil Arasu

Thomas Davis

Maria L Weetall

Don Corson

Jeff Campbell

William Lennox

Compounds that inhibit viral replication or the production of viral RNA or DNA or viral protein and compositions comprising such Compounds are described. Also described are methods of inhibiting or reducing viral replication or the production of viral RNA or DNA or viral protein using such Compounds, and methods for treating viral infections, such as an RNA virus belonging to the family Coronaviridae, involving the administration of such Compounds. The Compounds may be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatments.

Method of inhibiting or reducing a viral infection

Compounds, such as compounds of Formula (I), that selectively inhibit pathological production of human vascular endothelial growth factor (VEGF) and compositions comprising such Compounds are described. Compounds that inhibit viral replication or the production of viral RNA or DNA or viral protein and compositions comprising such Compounds are described. Also described are methods of reducing VEGF using such Compounds and methods for treating cancer and non-neoplastic conditions involving the administration of such Compounds. Further described are methods of inhibiting viral replication or the production of viral RNA or DNA or viral protein using such Compounds and methods for treating viral infections involving the administration of such Compounds. The Compounds may be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatments. 

Methods for treating cancer and non-neoplastic conditions

Growing community of inventors

Scranton, PA, United States of America

Jason D Graci