Life Technologies Corporation

Thermo Electron Led Gmbh

Jason D Brown

Clinton C Staheli

Nephi D Jones

Anthony D Meeks

Christopher D Brau

Steven R Kjar

Jeffery O Brown

Norman Ballhause

Hugh H Tansey, Iii

Romana Hinz

Ileana Place

Modular impeller

A method for culturing a microbial or cellular seed culture includes positioning a first flexible bag within a chamber of a first retainer, the first retainer being secured to a mixer table. A culture is produced within a compartment of the flexible bag, the culture comprising a growth media and a microbial or cellular starter culture added thereto. The mixer table is activated so that the culture is mixed within the compartment of the first flexible bag while the microbes or cells of the culture grow, the culture having a maximum volume of less than 10 liters.

Methods and systems for culturing microbial and cellular seed cultures

A condenser bag includes a body bounding a channel that extends between an inlet opening at a first end and an outlet opening at an opposing second end, the body being comprised of a polymeric film; an intake port bounding a port opening that extends therethrough, the intake port being directly physically secured to the first end of the body so that the port opening communicates with the channel of the body; and a tubular transfer line having a first end directly mechanically coupled with the body at a first location located between the inlet opening and the outlet opening so as to communicate with the channel and an opposing second end directly mechanically coupled to the intake port so as to communicate with the port opening thereof.

Condenser bag for processing a fluid

A mixing system for mixing a liquid includes a first impeller segment having a first mount and a first mixing blade secured to the first mount and a second impeller segment having a second mount and a first mixing blade secured to the second mount, the second impeller segment being separate and discrete from the first impeller segment. One or more drive members are secured to the first impeller segment and the second impeller segment for concurrently rotating the first impeller segment and the second impeller segment about a rotational axis. The first impeller segment and the second impeller segment are secured to the one or more drive members so that a plane extending normal to the axis of rotation intersects with the first mixing blade of the first impeller segment and the first mixing blade of the second impeller segment.

Fluid mixing systems with modular impellers and related methods

A method for filtering a gas comprises passing a gas through a compartment of a filter assembly, the filter assembly comprising: an inlet opening; a first outlet opening; a casing comprising polymeric film and bounding the compartment, the compartment communicating with the inlet opening and the first outlet opening; and a first filter at least partially disposed within the compartment. The method further comprising forming a first seal across a first section of the casing at a location between the inlet opening and the first filter to form a first sub-compartment within the casing and severing the casing at a first location.

Methods for gas filtration in fluid processing systems

A method for separating a biological suspension includes dispensing a liquid suspension comprised of cells or microorganisms from a bioreactor or fermenter into a sterile compartment of a first bag assembly, the first bag assembly including a collapsible bag having of one or more sheets of flexible film. The compartment of the first bag assembly is sealed closed. The first bag assembly, either with or without a manifold fluid coupled therewith, is then rotated, such as by using a centrifuge, so that the liquid suspension separates within the compartment into a pellet comprised of the cells or microorganisms and a liquid supernatant.

Single-use centrifuge containers for separating biological suspensions and methods of use

A method for filtering a gas includes passing a gas into a compartment of a casing that includes a polymeric film, the casing having: a first sleeve having a first outlet opening, a first filter being at least partially disposed within the first sleeve so that gas passing through the first sleeve must pass through the first filter; and a second sleeve having an second outlet opening, a second filter being at least partially disposed within the second sleeve so that gas passing through the second sleeve must pass through the second filter, the second sleeve being closed so that the gas passing into the compartment of the casing passes through the first sleeve and the first filter and directly contacts at least a portion of the first sleeve comprised of the polymeric film but does not pass through the second sleeve. Opening the second sleeve when a predetermined condition is met so that the gas passes through the second sleeve and the second filter.

Methods for gas filteration in fluid processing systems

A condenser system includes a collapsible container bag bounding a compartment and having an upper end and an opposing lower end, the container bag being formed of a polymeric film and being adapted to hold a fluid. A condenser bag is formed of a polymeric film and bounds a channel that extends between a first end and an opposing second end, the first end of the condenser bag being fluid coupled with the upper end of the container bag. A tubular transfer line has a first end coupled with the condenser bag at a first location so as to communicate with the channel and an opposing second end coupled with the condenser bag at a second location located between the container bag and the first location so as to communicate with the channel.

Condenser systems for processing a fluid

A filter assembly includes a casing having of a polymeric film and bounding a compartment, the casing having an inlet opening communicating with the compartment and a first outlet opening communicating with the compartment. A first filter includes a porous filter body through which gas can pass and has a pore size smaller than 1 &#x3bc;m, the first filter being coupled with the casing so that the filter body is at least partially disposed within compartment of the casing and so that gas passing through the compartment of the casing from the inlet opening to the first outlet opening must pass through the filter body.

Gas filter systems for fluid processing systems

A condenser bag includes a body bounding a channel that extends between an inlet opening at a first end and an outlet opening and an opposing second end, the body being comprised of a polymeric film. An intake port is secured to the body at the inlet opening and bounds an port opening that extends therethrough and communicates with the channel. A tubular transfer line has a first end coupled with the body so as to communicate with the channel at a first location located between the inlet opening and the outlet opening and an opposing second end coupled with either the intake port so as to communicate with the port opening therein or with the body so as to communicate with the channel at a second location located between the intake port and the first location.

Condenser systems for fluid processing systems

A foam sensor system includes a flexible bag comprised of a polymeric material and bounding a compartment. A foam sensor assembly is mounted on the flexible bag and includes a foam contact disposed within the compartment of the flexible bag. A ground assembly is mounted on the flexible bag and includes a ground contact disposed within the compartment of the flexible bag, the foam sensor assembly and the ground assembly being configured so that an electrical potential can be applied between the foam contact and the ground contact.

Growing community of inventors

Logan, UT, United States of America

Jason D Brown