Cephalon, Inc.

Thru Tubing Solutions, Inc.

Jason Burke

Bruce D Dorsey

Tao Guo

Gregory R Ott

Craig A Zificsak

Diane E Gingrich

Karen L Milkiewicz

Benjamin J Dugan

Theodore L Underiner

Gregory J Wells

Gulzar Ahmed

Matthew A Curry

Tho V Thieu

Daming Feng

Roger Lynn Schultz

Koc-Kan Ho

Henry Joseph Breslin

Rabindranath Tripathy

James L Diebold

Keith S Learn

Eugen F Mesaros

Joseph Lisko

Jay P Theroff

Rong-qiang Liu

Brett A Fears

Linda Weinberg

Jason C Wagner

Ming You

Adolph Bohnstedt

Joseph G Lisko

Jonathan Parrish

Rong-Qiang Liu

Karen Milkiewicz

This disclosure is related to a perforator tool and a method of using the perforator tool to perforate a formation. The perforator tool can include a first and second sleeve and optionally a third sleeve. The perforator tool can also include at least one perforation opening and at least one circulation port. The sleeves are slidably disposed within the perforator tool and can be displaced to permit perforation of the formation, block the perforation openings and open circulation ports.

Drill pipe perforator apparatus and method of use

The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R, R, R, R, R, A, A, A, A, and A, are as defined herein. The compounds of formula I or II have ALK and/or c-Met inhibitory activity, and may be used to treat proliferative disorders.

Fused bicyclic derivatives of 2,4-diaminopyrimidine as ALK and c-MET inhibitors

The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R, R, R, R, R, A, A, A, A, and A, are as defined herein. The compounds of formula I or II have ALK and/or c-Met inhibitory activity, and may be used to treat proliferative disorders. 

Fused bicyclic derivatives of 2,4-diaminopyrimidine as ALK and c-Met inhibitors

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Charlottesville, VA, United States of America

Jason Burke