Evonik Degussa Gmbh

Evonik Operations Gmbh

Technische Universitat Munchen

Jasmin Corthals

Steffen Schaffer

Mirja Wessel

Hans-Georg Joerg Hennemann

Thomas Haas

Harald Haeger

Arne Skerra

Martin Roos

Jan Christoph Pfeffer

Wolfgang Kroutil

Harald Häger

Liv Reinecke

Frank Erhardt

Katrin Grammann

Jan Wolter

Markus Pötter

Michael Volland

Sabine Hafkemeyer

Eva-Maria Eckl

Silvana Roeder

Katharina Berse

Nicole Potgrave

Harald Hager

Maik Olfert

Markus PÖTTER

A process for producing alanine, including culturing a cell under aerobic conditions in an aqueous phase in the presence of an inorganic nitrogen source, and then contacting the aqueous phase and the cell cultured in the aqueous phase with a hydrophobic organic phase. The cell is a prokaryotic or a lower eukaryotic cell and expresses a recombinant alanine dehydrogenase.

Method for aerobically producing alanine or a compound produced using alanine

The invention relates to a whole-cell catalyst which expresses a recombinant &#x3b1;-dioxygenase or the combination of a recombinant fatty acid reductase and a phosphopantetheinyl transferase which phosphopantetheinylates the fatty acid reductase, and which expresses, in addition to the &#x3b1;-dioxygenase and/or the combination of fatty acid reductase and phosphopantetheinyl transferase, a transaminase, wherein the phosphopantetheinyl transferase and/or transaminase is preferably recombinant; and also to a process for converting a carboxylic acid or dicarboxylic acid or a monoester thereof to an amine or diamine, comprising the steps of contacting the carboxylic acid or dicarboxylic acid or the monoester thereof with a phosphopantetheinylated fatty acid reductase or an &#x3b1;-dioxygenase and contacting the product with a transaminase.

Producing amines and diamines from a carboxylic acid or dicarboxylic acid or a monoester thereof

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Bochum, Germany

Jasmin Corthals