Ratiopharm Gmbh

Teva Pharmaceutical Industries Limited

Jaroslav Frantisek

Jiri Stohandl

Winfried Ness

Vinod Kumar Kansal

Armin Boerner

Vitali Tararov

Dhirenkumar Natvarial Mistry

Sanjay Vasoya

Gerd Koenig

Andrei Korostylev

Ghanshyam Pandey

Pavel Bobal

Amit Taneja

Kane Denike

Pramod Kadappa Shindey

Nicolas Jeker

The present invention is related to new intermediates and processes for preparing Ticagrelor disclosed in this patent application. One of the embodiments of the invention provides a process for preparing Ticagrelor of Formula I, comprising coupling a compound of Formula VI, with a compound of Formula IX, 

Intermediates and processes for preparing Ticagrelor

The present invention relates to a process for preparing pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly to improved synthetic methods for preparing 3,5-dihydroxy-7-pyrrol-1-yl heptanoic acids from 1,4-diketo starting materials. The invention further relates to intermediates in this process formula (I). 

Process for preparing pyrrole derivatives and intermediates

The present invention relates to processes for preparing a compound of the general formula (Ia) wherein X is a halogen atom, or a pharmaceutically acceptable salt thereof, wherein a compound of the formula (II) wherein X is as defined above and Y and Z independently represent a leaving group each, is reacted with an optically active amino alcohol to form a first mixture of diastereomers.

Stereoselective method for the production of (R)-Dimepranol

Stereoselective method for the production of Clopidogrel

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Brno, Czechia

Jaroslav Frantisek