Wallac Oy

Jarmo Nurmi

Timo E Oikari

Jarmo Sakari Korpi

Kenneth C Rundt

Raimo Harju

Markku Ojala

Timo Salminen

Aarne Heinonen

Janne Salonen

Markku Varjonen

Juha Karunen

Ilari Torsti

Paul White

Mikko V&auml;is&auml;l&auml;

Pertti Mantynen

Lauri Kaihola

Instrumentation and a method for efficient and reliable assaying and measuring samples. The teachings include an automated self-contained instrument, wherein the samples are located on wells of sample plates, and the instrument includes a plurality of units for processing or storing sample plates. The instrument may includes at least one dispensing unit for dispensing reagents or other assay components to the sample wells, at least two units for simultaneously processing or storing a plurality of sample plates, at least one unit for removing substance from the sample wells, and one or several measurement units for optically measuring samples in at least two measurement modes. Further, the instrument includes a manipulator for moving the sample plates in three orthogonal directions or combinations thereof and for rotating the sample plates in relation to a vertical axis for transferring the sample plates to the units.

Automated instrumentation and method for measurements of samples

An imaging device for biochemical or medical samples, the pulse mode light source of which incorporates flash lamps and a rotating mirror in an inclined position, the said mirror reflecting the light emitted by each flash lamp in turn along the same optical path to the sample. The flash lamps are switched on alternately in phases and synchronised with the rotating mirror and the emission light chopper, which comprises two rotating discs. The turning mirror directs the light at the sample from above and/or below, in which case a double-acting transparent scattering plate can be used.

Sample imaging device

A gain stabilization system for photomultiplier tubes using a pulsed light source, preferably a light emitting diode (LED), the signal of which is detected at the cathode and at the anode. The gain of photomultiplier tube is stabilized by keeping the ratio between the two signals constant.

Photomultiplier having gain stabilization means

Method for use in liquid scintillation counting for detecting, recording

The invention relates to a liquid scintillation counter comprising at least two photodetectors (2,3) for viewing a scintillation solution (1) in which both real multiphoton events and single photon events take place, and producing logic pulses and amplitude pulses in correspondence to these events, the amplitude of these amplitude pulses being a function of the number of photons that reach the photodetectors (2,3) for each of said events. According to the invention there are provided means (10) for delaying the logic pulses from one of said photodetectors, means (11) for either delaying or prolonging the amplitude pulses from the same photodetector, a coincidence analyzer for analyzing by means of the undelayed logic pulses and said delayed logic pulses whether said delayed or prolonged amplitude pulses are coincident within a predetermined coincidence resolving time with the undelayed or prolonged amplitude pulses from the other photodetector, and means for determining the number of these coincidences in a plurality of pulse amplitude intervals.

Liquid scintillation counter

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Kuusisto, Finland

Jarmo Nurmi